Exosomes are a subset of extracellular vesicles with an average diameter of~ 100nm.
Exosomes are released by all cells through an endosome-dependent pathway and carry …

The pathogenesis of preeclampsia begins when a fertilized egg infiltrates the decidua,
resulting in implantation failure (eg, due to extravillous trophoblast infiltration disturbance …

The aim of the study was to verify if quantification of placental specific C19MC microRNAs in
plasma exosomes would be able to differentiate during the early stages of gestation …

Serving as the interface between fetal and maternal circulation, the placenta plays a critical
role in fetal growth and development. Placental exosomes are small membrane-bound …

Pre-eclampsia (PE) is a systemic maternal syndrome affecting 2-8% of pregnancies
worldwide and involving poor placental perfusion and impaired blood supply to the foetus. It …

In placental mammals, reproductive success, and maternal-fetal health substantially depend
on a well-being placenta, the interface between the fetus and the mother. Disorders in …

Preeclampsia affects about 3–8% of all pregnancies. It represents a complex and
multifaceted syndrome with at least several potential pathways leading to the development …

It is now well-established that microRNAs (miRNAs) are important regulators of gene
expression. The role of miRNAs in placental development and trophoblast function is …

Preeclampsia and other hypertensive disorders of pregnancy are major contributors to
maternal morbidity and mortality worldwide. This group of disorders includes chronic …

Abstract Pre-eclampsia (PE), associated with placental malperfusion, is the primary reason
for maternal and perinatal mortality and morbidity that can cause vascular endothelial injury …