Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free
apolipoprotein AI (apoA-I) and apolipoprotein E (apoE). ABCA1 is an essential regulator of …

Introduction The adenosine triphosphate-binding cassette transporter A1 (ABCA1) is a major
cholesterol transporter highly expressed in the liver and brain. In the brain, ABCA1 lipidates …

Alzheimer's disease (AD) has been associated with dysregulation of brain cholesterol
homeostasis. Proprotein convertase subtilisin/kexin type 9 (PCSK9), beyond the known role …

High‐density lipoproteins (HDL) are a heterogeneous class of molecules whose main
function is to remove excess cholesterol through a mechanism called reverse transport, in …

We preformed this meta-analysis to investigate the influence of ABCA1 (ATP-binding
cassette sub-family A member 1) rs2422493 (C-477T), rs1800977 (C-14T), rs2066718 …

The ATP-binding cassette, sub-family A, member 1 gene (ABCA1) is a relevant positional
and functional candidate gene for Alzheimer's disease (AD). A case-control association …

Background ABCA1 R219K single-nucleotide polymorphisms (SNPs) was related to
Alzheimer disease (AD) but not Parkinson disease (PD). Here, we analyzed the associations …

Conflicting evidence was found about the relationship between lipid profiles and R219K
polymorphism in adenosine triphosphate-binding cassette exporter A1 (ABCA1) gene. In …

The ATP-binding cassette A1 (ABCA1) transporter plays a major role in the efflux of lipids by
mediating the cellular transport of phospholipids and cholesterol to lipid-poor/lipid-free …