Microvascular destabilization and intricated network of the cytokines in diabetic retinopathy: from the perspective of cellular and molecular components

X Sheng, C Zhang, J Zhao, J Xu, P Zhang, Q Ding… - Cell & Bioscience, 2024 - Springer
Microvascular destabilization is the primary cause of the inner blood-retinal barrier (iBRB)
breakdown and increased vascular leakage in diabetic retinopathy (DR). Microvascular …

Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications

D Knežević, B Ćurko-Cofek, T Batinac… - Journal of …, 2023 - mdpi.com
Cardiac surgery is one of the highest-risk procedures, usually involving cardiopulmonary
bypass and commonly inducing endothelial injury that contributes to the development of …

β-Asarone alleviates high-glucose-induced oxidative damage via inhibition of ROS generation and inactivation of the NF-κB/NLRP3 inflammasome pathway in human …

C Park, HJ Cha, H Hwangbo, EJ Bang, SH Hong… - Antioxidants, 2023 - mdpi.com
Diabetic retinopathy (DR) is the leading cause of vision loss and a major complication of
diabetes. Hyperglycemia-induced accumulation of reactive oxygen species (ROS) is an …

[HTML][HTML] The Crucial Triad: Endothelial Glycocalyx, Oxidative Stress, and Inflammation in Cardiac Surgery—Exploring the Molecular Connections

B Ćurko-Cofek, M Jenko, G Taleska Stupica… - International journal of …, 2024 - mdpi.com
Since its introduction, the number of heart surgeries has risen continuously. It is a high-risk
procedure, usually involving cardiopulmonary bypass, which is associated with an …

[HTML][HTML] The application of medicinal fungi from the subphylum Ascomycota in the treatment of type 2 diabetes

Y Jiang, H Song, G Zhang, J Ling - Journal of Future Foods, 2025 - Elsevier
Diabetes is a chronic metabolic disease with an increasing incidence rate year by year. It
severely diminishes the quality of life for individuals, reduces life expectancy, and poses a …

Molecular implications of glycosaminoglycans in diabetes pharmacotherapy

T Waseem, M Ahmed, TA Rajput, MM Babar - International Journal of …, 2023 - Elsevier
Diabetes mellitus causes a wide range of metabolic derangements with multiple organ
damage. The microvascular and macrovascular complications of diabetes result partly from …

[HTML][HTML] Dulaglutide and Dapagliflozin Combination Concurrently Improves the Endothelial Glycocalyx and Vascular and Myocardial Function in Patients with T2DM …

E Korakas, J Thymis, E Oikonomou… - Journal of Clinical …, 2024 - mdpi.com
Background: The association between diabetic nephropathy and arterial elasticity and
endothelial function is well established. In this study, we compared the effect of the …

Insights into the Molecular Mechanism of Endothelial Glycocalyx Dysfunction during Heart Surgery

A Kršek, L Batičić, B Ćurko-Cofek, T Batinac… - Current Issues in …, 2024 - mdpi.com
The endothelial glycocalyx (EGC) is a layer of proteoglycans (associated with
glycosaminoglycans) and glycoproteins, which adsorbs plasma proteins on the luminal …

Association between rest-activity rhythm and diabetic retinopathy among US middle-age and older diabetic adults

Z Wang, M Wu, H Li, B Zheng - Frontiers in Endocrinology, 2024 - frontiersin.org
Background The disruption of circadian rhythm has been reported to aggravate the
progression of diabetic retinopathy (DR). Rest-activity rhythm (RAR) is a widely used method …

Stevia extract safeguards rats from diabetic renal injury by mitigating markers of inflammation, oxidative stress, and apoptosis

FM Othman, MR El-Sawi, SM Shabana - Toxicology and Environmental …, 2023 - Springer
Objective This study will figure out if stevia extract, a herb with anti-inflammatory and
antioxidant characteristics, is effective in treating diabetic nephropathy (DN) and protecting …