The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …

Histone modifications are key epigenetic regulatory features that have important roles in
many cellular events. Lysine methylations mark various sites on the tail and globular …

To satisfy its high energetic demand, the brain depends on the metabolic cooperation of
various cell types,–. For example, astrocytic-derived lactate sustains memory consolidation …

The pentose phosphate pathway (PPP) is a branch from glycolysis that begins from glucose-
6-phosphate (G6P) and ends up with fructose-6-phosphate (F6P) and glyceraldehyde-3 …

Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the
pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP …

Highlights•The first comprehensive compilation of Smyd proteins critical role in cardiac and
skeletal muscle.•Demonstrates the Smyd family's unique ability to regulate transcription …

Abstract miRNAs, sorting as non-coding RNAs, are differentially expressed in breast tumor
and act as tumor promoters or suppressors. miR-206 could suppress the progression of …

Mitochondrial reactive oxygen species (mROS) have been generally considered harmful
byproducts wanted to clear when elevated to avoid brain damage. However, the abundance …

RNA is likely to be the most rediscovered macromolecule in biology. Periodically, new non-
canonical functions have been ascribed to RNA, such as the ability to act as a catalytic …

Cancer cells alter their metabolism to support the uninterrupted supply of biosynthetic
molecules required for continuous proliferation. Glucose metabolism is frequently …