5-fluorouracil and cardiotoxicity: a review
JD Sara, J Kaur, R Khodadadi… - … in medical oncology, 2018 - journals.sagepub.com
Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of
chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic …
chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic …
[HTML][HTML] Cardiovascular complications of metastatic colorectal cancer treatment
K Keramida, G Charalampopoulos… - Journal of …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common malignancy in men and the second in
women and the fourth cause of cancer death. Survival rates decrease greatly according to …
women and the fourth cause of cancer death. Survival rates decrease greatly according to …
Raltitrexed induces mitochondrial-mediated apoptosis in SGC7901 human gastric cancer cells
S Xue, YX Chen, SK Qin, AZ Yang… - Molecular …, 2014 - spandidos-publications.com
Raltitrexed is a specific inhibitor of thymidylate synthase (TS), which has been considered as
a potential chemotherapeutic agent for the treatment of advanced gastric cancer. In the …
a potential chemotherapeutic agent for the treatment of advanced gastric cancer. In the …
Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4
C Hu, X Chen, X Lin, J Dai, J Yu - BMC Pharmacology and Toxicology, 2022 - Springer
Background Raltitrexed is a specific inhibitor of thymidylate synthase and a potential
chemotherapeutic agent for the treatment of advanced gastric cancer. In this study, we …
chemotherapeutic agent for the treatment of advanced gastric cancer. In this study, we …
雷替曲塞对人胃癌裸鼠移植瘤生长的影响及其机制
洪雷， 李华， 常靓， 刘巍 - 中国肿瘤临床, 2014 - cjco.cn
雷替曲塞对人胃癌裸鼠移植瘤生长的影响及其机制 首页 期刊简介 1.期刊介绍 2.获奖情况
编委会 期刊在线 1.最新录用 2.优先发表 3.当期目录 4.过刊浏览 视频合辑 在线投稿 1.投稿须知 …
编委会 期刊在线 1.最新录用 2.优先发表 3.当期目录 4.过刊浏览 视频合辑 在线投稿 1.投稿须知 …
Clinical observations on associations between the UGT1A1 genotype and severe toxicity of irinotecan
YY Lu, XE Huang, XY Wu, J Cao, J Liu… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: Severe toxicity is commonly observed in cancer patients receiving irinotecan
(CPT-11) UDPglucuronosyltransferase1A1 (UGT1A1) catalyzes the glucuronidation of the …
(CPT-11) UDPglucuronosyltransferase1A1 (UGT1A1) catalyzes the glucuronidation of the …
转移性结直肠癌三线化疗研究现状
刘静， 刘云鹏 - 肿瘤综合治疗电子杂志, 2018 - jmcm2018.com
随着新型抗肿瘤药物的不断研发和多学科诊疗模式的普及应用, 转移性结直肠癌患者的生存时间
显著延长. 但是, 多线化疗失败后的治疗仍面临巨大挑战. 一些新型靶向药物显示出一定疗效 …
显著延长. 但是, 多线化疗失败后的治疗仍面临巨大挑战. 一些新型靶向药物显示出一定疗效 …
A case–control study on the correlation between thymidylate synthase gene polymorphisms and raltitrexed treatment combined with transcatheter arterial …
C Qi, H Gao, S Li, H Zong, H Hao… - Genetic Testing and …, 2020 - liebertpub.com
Background: To study the effect of single nucleotide polymorphisms (SNPs) in the
thymidylate synthase (TYMS) gene for their value in predicting the efficacy of raltitrexed …
thymidylate synthase (TYMS) gene for their value in predicting the efficacy of raltitrexed …