COVID-19 and cardiovascular disease: from bench to bedside

MK Chung, DA Zidar, MR Bristow, SJ Cameron… - Circulation …, 2021 - Am Heart Assoc
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential
consequences on the cardiovascular health of millions of people who survive infection …

[HTML][HTML] COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

[HTML][HTML] Is COVID-19 gender-sensitive?

S Mukherjee, K Pahan - Journal of Neuroimmune Pharmacology, 2021 - Springer
While clinical characteristics exhibit that susceptibility to COVID-19 infection is equally likely
between males and females, clinical outcomes show that males experience both a higher …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

[HTML][HTML] COVID-19-associated vasculitis and vasculopathy

RC Becker - Journal of thrombosis and thrombolysis, 2020 - Springer
The COVID-19 pandemic now totaling 13,000,000 cases and over 571,000 deaths has
continued to teach the medical, scientific and lay communities about viral infectious disease …

[HTML][HTML] Role of cardiac macrophages on cardiac inflammation, fibrosis and tissue repair

WP Lafuse, DJ Wozniak, MVS Rajaram - Cells, 2020 - mdpi.com
The immune system plays a pivotal role in the initiation, development and resolution of
inflammation following insult or damage to organs. The heart is a vital organ which supplies …

[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic

GY Oudit, K Wang, A Viveiros, MJ Kellner… - Cell, 2023 - cell.com
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …

[HTML][HTML] Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva… - Nature, 2021 - nature.com
The COVID-19 pandemic is the third outbreak this century of a zoonotic disease caused by a
coronavirus, following the emergence of severe acute respiratory syndrome (SARS) in 2003 …

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

Y Li, DM Renner, CE Comar… - Proceedings of the …, 2021 - National Acad Sciences
Coronaviruses are adept at evading host antiviral pathways induced by viral double-
stranded RNA, including interferon (IFN) signaling, oligoadenylate synthetase–ribonuclease …

[HTML][HTML] Cardiovascular manifestations of COVID-19 infection

A Magadum, R Kishore - Cells, 2020 - mdpi.com
SARS-CoV-2 induced the novel coronavirus disease (COVID-19) outbreak, the most
significant medical challenge in the last century. COVID-19 is associated with notable …