[HTML][HTML] Advances in cancer therapy: A comprehensive review of CDK and EGFR inhibitors

M Hawash - Cells, 2024 - mdpi.com
Protein kinases have essential responsibilities in controlling several cellular processes, and
their abnormal regulation is strongly related to the development of cancer. The …

Star wars against leukemia: attacking the clones

MM Toma, T Skorski - Leukemia, 2024 - nature.com
Leukemia, although most likely starts as a monoclonal genetic/epigenetic anomaly, is a
polyclonal disease at manifestation. This polyclonal nature results from ongoing …

Layer-by-layer fabrication of covalent organic frameworks on stainless steel needles as solid-phase microextraction probe coupled with electrospray ionization mass …

H Li, X Shi, H Su, S Wang, J Lin, Z Lin, Z Cai - Journal of Chromatography A, 2024 - Elsevier
Sunitinib, N-desmethyl imatinib, dasatinib, imatinib, and bosutinib are tyrosine kinase
inhibitors (TKIs) that are commonly employed in the treatment of a multitude of cancers …

Analytical quality by design-compliant development of quantitative 1H-and 19F-nuclear magnetic resonance methods for the analytical evaluation of the anti-cancer …

MH Hassan, RAI Abou-Elkhair, AEA Hassan… - Microchemical …, 2025 - Elsevier
This study introduces a novel application of Analytical Quality by Design (AQbD) principles
to develop 1 H-qNMR and 19 F-qNMR methods for quantifying sorafenib (SORA) in its pure …

Synthesis and anti-tumor activity of new benzofuran-based chalcone derivatives as potent VEGFR-2 inhibitors

C Zhang, Y Liu, X Zhang, C Wan, Z Mao - RSC Medicinal Chemistry, 2025 - pubs.rsc.org
Cancer is one of the most significant public health problems worldwide, and the discovery
and development of efficient VEGFR-2 inhibitors has been a research hotspot in cancer …

Emerging Techniques in Cancer Therapy: Precision Targeting for Improved Outcomes

RB Kargbo - ACS Medicinal Chemistry Letters, 2024 - ACS Publications
The continuous evolution of cancer therapy has driven the exploration of novel strategies to
improve treatment specificity and efficacy while minimizing adverse effects. This article …

Novel TYK2 Inhibitors for Treating Autoimmune and Inflammatory Diseases

RW Sabnis - ACS Medicinal Chemistry Letters, 2024 - ACS Publications
Novel TYK2 Inhibitors for Treating Autoimmune and Inflammatory Diseases Page 1 Novel TYK2
Inhibitors for Treating Autoimmune and Inflammatory Diseases Ram W. Sabnis* Cite This …