Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

Microbiota-brain-gut axis and neurodegenerative diseases

EMM Quigley - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review The purposes of this review were as follows: first, to provide an
overview of the gut microbiota and its interactions with the gut and the central nervous …

Probiotics, prebiotics and epithelial tight junctions: a promising approach to modulate intestinal barrier function

EC Rose, J Odle, AT Blikslager, AL Ziegler - International journal of …, 2021 - mdpi.com
Disruptions in the intestinal epithelial barrier can result in devastating consequences and a
multitude of disease syndromes, particularly among preterm neonates. The association …

Dysbiosis of Gut Microbiota from the Perspective of the Gut–Brain Axis: Role in the Provocation of Neurological Disorders

M Kandpal, O Indari, B Baral, S Jakhmola, D Tiwari… - Metabolites, 2022 - mdpi.com
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Gut microbes and health: a focus on the mechanisms linking microbes, obesity, and related disorders

M Rastelli, C Knauf, PD Cani - Obesity, 2018 - Wiley Online Library
The past decade has been characterized by tremendous progress in the field of the gut
microbiota and its impact on host metabolism. Although numerous studies show a strong …

Neuroimmunophysiology of the gut: advances and emerging concepts focusing on the epithelium

KA Sharkey, PL Beck, DM McKay - Nature reviews Gastroenterology & …, 2018 - nature.com
The epithelial lining of the gastrointestinal tract serves as the interface for digestion and
absorption of nutrients and water and as a defensive barrier. The defensive functions of the …

The gut microbiome feelings of the brain: a perspective for non-microbiologists

A Lerner, S Neidhöfer, T Matthias - Microorganisms, 2017 - mdpi.com
Objectives: To comprehensively review the scientific knowledge on the gut–brain axis.
Methods: Various publications on the gut–brain axis, until 31 July 2017, were screened …

Antibiotic‐induced dysbiosis of the microbiota impairs gut neuromuscular function in juvenile mice

V Caputi, I Marsilio, V Filpa, S Cerantola… - British journal of …, 2017 - Wiley Online Library
Background and Purpose Gut microbiota is essential for the development of the
gastrointestinal system, including the enteric nervous system (ENS). Perturbations of gut …

Gut microbiota regulates neuropathic pain: potential mechanisms and therapeutic strategy

B Lin, Y Wang, P Zhang, Y Yuan, Y Zhang… - The journal of headache …, 2020 - Springer
Neuropathic pain (NP) is a sustained and nonreversible condition characterized by long-
term devastating physical and psychological damage. Therefore, it is urgent to identify an …

Enteric glia: a new player in abdominal pain

W Morales-Soto, BD Gulbransen - Cellular and molecular gastroenterology …, 2019 - Elsevier
Chronic abdominal pain is the most common gastrointestinal issue and contributes to the
pathophysiology of functional bowel disorders and inflammatory bowel disease. Current …