Channel innovations for inertial microfluidics

W Tang, S Zhu, D Jiang, L Zhu, J Yang, N Xiang - Lab on a Chip, 2020 - pubs.rsc.org
Inertial microfluidics has gained significant attention since first being proposed in 2007
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …

Recent advances in acoustofluidic separation technology in biology

Y Fan, X Wang, J Ren, F Lin, J Wu - Microsystems & Nanoengineering, 2022 - nature.com
Acoustofluidic separation of cells and particles is an emerging technology that integrates
acoustics and microfluidics. In the last decade, this technology has attracted significant …

Recent advances in manipulation of micro-and nano-objects with magnetic fields at small scales

Q Cao, Q Fan, Q Chen, C Liu, X Han, L Li - Materials Horizons, 2020 - pubs.rsc.org
Manipulation of micro-and nano-objects has been widely studied in the past two decades
due to its potential applications in various fields. In this review, we focus primarily on …

Methodologies, technologies, and strategies for acoustic streaming-based acoustofluidics

M Stringer, Z Zeng, X Zhang, Y Chai, W Li… - Applied Physics …, 2023 - pubs.aip.org
Acoustofluidics offers contact-free manipulation of particles and fluids, enabling their uses in
various life sciences, such as for biological and medical applications. Recently, there have …

Recent advances on magnetic nanobead based biosensors: From separation to detection

L Wang, J Lin - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Magnetic nanobeads have been widely used for magnetic separation, target labeling and
signal amplification in the development of various biosensors. This review summarized (1) …

Unconventional acoustic approaches for localized and designed micromanipulation

K Kolesnik, M Xu, PVS Lee, V Rajagopal, DJ Collins - Lab on a Chip, 2021 - pubs.rsc.org
Acoustic fields are ideal for micromanipulation, being biocompatible and with force gradients
approaching the scale of single cells. They have accordingly found use in a variety of …

Delivering the CRISPR/Cas9 system for engineering gene therapies: Recent cargo and delivery approaches for clinical translation

RA Foley, RA Sims, EC Duggan, JK Olmedo… - … in Bioengineering and …, 2022 - frontiersin.org
Clustered Regularly Interspaced Short Palindromic Repeats associated protein 9
(CRISPR/Cas9) has transformed our ability to edit the human genome selectively. This …

Inertial microfluidics for high-throughput cell analysis and detection: a review

Z Zhou, Y Chen, S Zhu, L Liu, Z Ni, N Xiang - Analyst, 2021 - pubs.rsc.org
Since it was first proposed in 2007, inertial microfluidics has been extensively studied in
terms of theory, design, fabrication, and application. In recent years, with the rapid …

On-chip integrated optical stretching and electrorotation enabling single-cell biophysical analysis

L Huang, F Liang, Y Feng, P Zhao… - Microsystems & …, 2020 - nature.com
Cells have different intrinsic markers such as mechanical and electrical properties, which
may be used as specific characteristics. Here, we present a microfluidic chip configured with …

Investigation on a cascaded inertial and acoustic microfluidic device for sheathless and label-free separation of circulating tumor cells

T Peng, J Qiang, S Yuan - Physics of Fluids, 2023 - pubs.aip.org
High-precision and high-purity acquisition of tumor cells from whole blood is vital for early
disease detection and diagnosis. Here, we investigated a cascaded inertial and acoustic …