Principles of TAVR valve design, modelling, and testing

OM Rotman, M Bianchi, RP Ghosh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Transcatheter aortic valve replacement (TAVR) has emerged as an effective
minimally-invasive alternative to surgical valve replacement in medium-to high-risk, elderly …

Transcatheter aortic valve thrombosis: a review of potential mechanisms

V Raghav, P Midha, R Sharma… - Journal of the …, 2021 - royalsocietypublishing.org
Transcatheter aortic valve (TAV) thrombosis has been recognized as a significant problem
that sometimes occurs as early as within 30 days after valve implantation, leading to …

[HTML][HTML] An in vitro evaluation of turbulence after transcatheter aortic valve implantation

H Hatoum, A Yousefi, S Lilly, P Maureira… - The Journal of thoracic …, 2018 - Elsevier
Background This study aimed at assessment of post-transcatheter aortic valve (TAV)
replacement hemodynamics and turbulence when a same-size SAPIEN 3 (Edwards …

Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Applications: In Vitro Hemodynamic Study

OM Rotman, B Kovarovic, WC Chiu, M Bianchi… - Annals of biomedical …, 2019 - Springer
Transcatheter aortic valve replacement (TAVR) is a minimally-invasive approach for treating
severe aortic stenosis. All clinically-used TAVR valves to date utilize chemically-fixed …

Turbulent systolic flow downstream of a bioprosthetic aortic valve: velocity spectra, wall shear stresses, and turbulent dissipation rates

B Becsek, L Pietrasanta, D Obrist - Frontiers in physiology, 2020 - frontiersin.org
Every year, a quarter million patients receive prosthetic heart valves in aortic valve
replacement therapy. Prosthetic heart valves are known to lead to turbulent blood flow. This …

Neosinus and sinus flow after self-expanding and balloon-expandable transcatheter aortic valve replacement

H Hatoum, SCM Gooden, J Sathananthan… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to evaluate flow dynamics in the aortic sinus and the
neosinus (NS) after transcatheter heart valve (THV) implantation in valve-in-valve (ViV) …

Transcatheter aortic valve replacement for structural degeneration of previously implanted transcatheter valves (TAVR-in-TAVR): a systematic review

M Gallo, LN Fovino, D Blitzer… - European Journal of …, 2022 - academic.oup.com
OBJECTIVES Transcatheter aortic valve replacement (TAVR) represents a valid treatment
for patients with aortic valve stenosis and high or intermediate surgical risk. However …

Predictive model for thrombus formation after transcatheter valve replacement

H Hatoum, S Singh-Gryzbon, F Esmailie… - Cardiovascular …, 2021 - Springer
Purpose Leaflet thrombosis is a significant adverse event after transcatheter aortic valve
(TAV) replacement (TAVR). The purpose of our study was to present a semi-empirical …

Impact of leaflet laceration on transcatheter aortic valve-in-valve washout: BASILICA to solve neosinus and sinus stasis

H Hatoum, P Maureira, S Lilly, LP Dasi - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: The aim of this study was to evaluate any potential leaflet washout benefits after
bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary …

Sinus hemodynamics variation with tilted transcatheter aortic valve deployments

H Hatoum, J Dollery, SM Lilly, JA Crestanello… - Annals of biomedical …, 2019 - Springer
Leaflet thrombosis is a complication associated with transcatheter aortic valve (TAV)
replacement (TAVR) correlated with sinus flow stasis. Sinus hemodynamics are important …