The natural polyamines putrescine, spermidine and spermine are in multiple ways involved
in cell growth and the maintenance of cell viability. In the course of the last 15 years more …

The year 2004 represents a milestone for the biosensor research community: in this year,
over 1000 articles were published describing experiments performed using commercially …

Breast cancer (BC) is a common disease that generally occurs in women over the age of 50,
and the risk is especially high for women over 60 years of age. One of the major BC …

NF-B is a versatile transcription factor that regulates a wide array of processes, including
inflammation and survival, and plays a critical role in the etiology of inflammatory lung …

Strategies to decrease intracellular polyamine levels have been studied for their efficacy in
reducing colorectal cancer (CRC) risk. A successful strategy combined agents that …

Spermine (SPM) and its precursor putrescine (PUT), regulated by ornithine decarboxylase
(ODC) and diamino-oxidase (DAO), are polyamines required for cell growth and …

Background Polyamines are important in cell growth and wound repair, but have also been
implicated in inflammation-induced carcinogenesis. Polyamine metabolism includes back …

In neoplasic cachexia, chemical mediators seem to act as initiators or perpetuators of this
process. Walker 256 cells, whose metabolic properties have so far been little studied with …

Purvalanol A is a specific CDK inhibitor which triggers apoptosis by causing cell cycle arrest
in cancer cells. Although it has strong apoptotic potential, the mechanistic action of …

The significant separate biochemical discoveries of pro-and anti-apoptotic-autophagy, and-
proliferative processes in normal and pathology cells were learned in detail from the point of …