Detection of biomarker using aptasensors to determine the type of diabetes

DE Mulyani, IP Maksum - Diagnostics, 2023 - mdpi.com
Diabetes mellitus (DM) is a metabolic disorder characterized by elevated blood glucose
levels. This disease is so serious that many experts refer to it as the “silent killer”. The early …

Molecular Dynamics Simulation of T10609C and C10676G Mutations of Mitochondrial ND4L Gene Associated With Proton Translocation in Type 2 Diabetes Mellitus …

W Destiarani, R Mulyani, M Yusuf… - … and Biology Insights, 2020 - journals.sagepub.com
The mutation rate of mitochondrial DNA (mtDNA) is 17 times higher than nuclear DNA, and
these mutations can cause mitochondrial disease in 1 of 10.000 people. The T10609C …

Molecular dynamics simulation of a tRNA-leucine dimer with an A3243G heteroplasmy mutation in human mitochondria using a secondary structure prediction …

IP Maksum, AF Maulana, M Yusuf… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
Mitochondrial DNA mutations, such as A3243G, can affect changes in the structure of
biomolecules, resulting in changes in the structure of Leucine transfer Ribose Nucleic Acid …

Bioinformatics Study of m.9053G>A Mutation at the ATP6 Gene in Relation to Type 2 Diabetes Mellitus and Cataract Diseases

I Permana Maksum, SR Saputra… - … and biology insights, 2017 - journals.sagepub.com
The mitochondrial disease often associated with various illnesses in relation to the activity of
cells metabolites and the synthesis of adenosine triphosphate (ATP), including alteration in …

Optimization of Aptamer-Based Electrochemical Biosensor for ATP Detection Using Screen-Printed Carbon Electrode/Gold Nanoparticles (SPCE/AuNP)

R Mulyani, N Yumna, IP Maksum… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
Electrochemical biosensors are used to detect adenosine triphosphate (ATP) levels, which
are involved in a variety of biological processes, such as regulating cellular metabolism and …

In silico study of aptamer specificity for detection of adenosine triphosphate (ATP) as biosensor development for mitochondria diabetes diagnosis

R Rustaman, RR Rahmawan… - … and Theoretical Chemistry, 2023 - dergipark.org.tr
Diabetes Mellitus (DM) is characterized by increased blood glucose levels. It is generally
caused by the pancreas' inability to produce insulin due to cell damage or insulin resistance …

Biosensor Elektrokimia untuk Memonitor Level Hemoglobin Terglikasi (HbA1c) pada Penyakit Diabetes Melitus

S Destiani, IP Maksum, YW Hartati - ALCHEMY Jurnal Penelitian …, 2023 - jurnal.uns.ac.id
Hiperglikemia merupakan ciri diabetes melitus, sekelompok penyakit metabolik yang
disebabkan oleh kelainan sekresi insulin, kerja insulin, atau keduanya. Hiperglikemia dapat …

Proposed molecular mechanism of non-competitive inhibition using molecular dynamics simulations between α-glucosidase enzyme and mangostin compound as …

AF Maulana, IP Maksum, S Sriwidodo… - Journal of Molecular …, 2024 - Springer
Method This research commenced with retrieving protein structures from the RCSB
database, generating the formation of ligands using the ChemDraw Professional software …

The Relation of Mitochondrial DNA Mutation with Mitochondrial Diseaseas in Coding Region

IP Maksum, SF Alchumaira, DS Kamara… - Procedia …, 2015 - Elsevier
Mitochondrial disorders are recognized in several metabolic and degenerative diseases,
aging and cancer. Mitochondrial functional deficiency maybe caused by a decrease in the …

[PDF][PDF] An Investigation of the Effect of T15458C and T15663C Mutations in the CYB Gene on Respiration via an In silico Method

R Mulyani, W Destiarani, UM Rahmawati… - J. Proteom …, 2020 - academia.edu
Diabetic mellitus and cataracts are common mitochondrial diseases in Indonesia, occurring
as a result of a lack of ATP, which is produced in mitochondria via oxidative phosphorylation …