Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

Optical coherence tomography (OCT) imaging has played a pivotal role in the field of retina.
This light-based, non-invasive imaging modality provides high-quality, cross-sectional …

Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

Purpose: By optical coherence tomography (OCT) imaging, hyperreflective foci (HRF)
indicate progression risk for advanced age-related macular degeneration (AMD) and are in …

Purpose: Basal linear deposit (BLinD) is a thin layer of soft drusen material. To elucidate the
biology of extracellular deposits conferring age-related macular degeneration (AMD) …

Optical coherence tomography (OCT) has become a novel approach to noninvasive imaging
in the past three decades, bringing a significant potential to biological research and medical …

We present a compact multi-modal and multi-scale retinal imaging instrument with an
angiographic functional extension for clinical use. The system integrates scanning laser …

Purpose: Despite the centrality of the retinal pigment epithelium (RPE) in vision and
retinopathy our picture of RPE morphology is incomplete. With a volumetric reconstruction of …

Purpose Melanotic cells with large spherical melanosomes, thought to originate from retinal
pigment epithelium (RPE), are found in eyes with neovascular age-related macular …

Line-scan OCT incorporated with adaptive optics (AO) offers high resolution, speed, and
sensitivity for imaging retinal structure and function in vivo. Here, we introduce its …