The maturation and functional characteristics of human induced pluripotent stem cell
(hiPSC)-cortical neurons has not been fully documented. This study developed a phenotypic …

Long‐term potentiation (LTP) is a highly studied cellular process, yet determining the
transduction and gamma aminobutyric acid (GABAergic) pathways that are the essential …

Background/Objectives: Dopamine dysfunction (DA) is a hallmark of many neurological
disorders. In this case, the mechanism of changes in dopamine transmission on behavior …

Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by memory loss
and cognitive decline. Among the suggested pathogenic mechanisms of AD, the cholinergic …

Glutamate is the most abundant excitatory neurotransmitter in the hippocampus where
mediates its actions by activating glutamate receptors. The activation of these receptors is …

Heavy metal contamination in aquatic environments plays an important role in the exposure
of humans to these toxicants. Among these pollutants, mercury (Hg) is one main concern …

Alcohol use disorder (AUD) differentially impacts men and women and a growing body of
evidence points to sex-dependent adaptations in a number of brain regions. In a prior study …

There are no clinical interventions to prevent post-injury epilepsy, a common and
devastating outcome after brain insults. Epileptogenic events that run from brain injury to …

Alzheimer's disease (AD) is commonly characterized by a loss of cognitive function due to
the deterioration of neuronal synapses from the presence of senile amyloid beta-42 (Aß42) …

Long-term potentiation (LTP) is a highly studied cellular process yet determining the
transduction and GABAergic pathways that are the essential vs. modulatory for LTP elicited …