Rational pharmacotherapy in infectious diseases: issues related to drug residues in edible animal tissues

L Canton, C Lanusse, L Moreno - Animals, 2021 - mdpi.com
Simple Summary Drug use is essential to treat diseases in food-producing animals. The
most widely used drugs are antiparasitics and antimicrobials. They contribute to …

Liquid chromatography–tandem mass spectrometry multiclass method for 46 antibiotics residues in milk and meat: development and validation

L Jank, MT Martins, JB Arsand, TMC Motta… - Food Analytical …, 2017 - Springer
A screening method for analysis of 46 antibiotics residues, belonging to different classes,
such as tetracyclines, sulfonamides, fluoroquinolones, β-lactams, cephalosporins …

Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment

M Li, R Gehring, JE Riviere, Z Lin - Food and chemical toxicology, 2017 - Elsevier
Penicillin G is a widely used antimicrobial in food-producing animals, and one of the most
predominant drug residues in animal-derived food products. Due to reduced sensitivity of …

Depletion study of enrofloxacin and its metabolite ciprofloxacin in edible tissues and feathers of white leghorn hens by liquid chromatography coupled with tandem …

B San Martín, J Cornejo, D Iragüen, H Hidalgo… - Journal of food …, 2007 - Elsevier
To ensure delivery of safe foods to consumers, withdrawal times for drugs must be respected
according to the maximum residual limits established by regulatory agencies. Because of …

Drug laws and regulations for sheep and goats

VR Fajt - Veterinary Clinics: Food Animal Practice, 2011 - vetfood.theclinics.com
2. Decision whether use of a drug would affect the pathophysiologic changes 3.
Identification of potential drugs that may produce the desired effect (this implies knowledge …

Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)

TL Leavens, LA Tell, LW Kissell, GW Smith… - Food Additives & …, 2014 - Taylor & Francis
Frequent violation of flunixin residues in tissues from cattle has been attributed to non-
compliance with the USFDA-approved route of administration and withdrawal time …

An interactive generic physiologically based pharmacokinetic (igPBPK) modeling platform to predict drug withdrawal intervals in cattle and swine: A case study on …

WC Chou, LA Tell, RE Baynes, JL Davis… - Toxicological …, 2022 - academic.oup.com
Violative chemical residues in edible tissues from food-producing animals are of global
public health concern. Great efforts have been made to develop physiologically based …

Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based …

M Li, YH Cheng, JT Chittenden, RE Baynes, LA Tell… - Archives of …, 2019 - Springer
Violative chemical residues in animal-derived food products affect food safety globally and
have impact on the trade of international agricultural products. The Food Animal Residue …

Inappropriate usage of selected antimicrobials: Comparative residue proportions in rural and urban beef in Uganda

Y Basulira, SA Olet, PE Alele - PLoS One, 2019 - journals.plos.org
Introduction In most developing countries like Uganda, antimicrobials including β-lactams
and tetracyclines are used indiscriminately in livestock. When livestock get sick and …

[HTML][HTML] Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle

LW Kissell, GW Smith, TL Leavens, RE Baynes… - Journal of dairy …, 2012 - Elsevier
The objective of this study was to determine if the plasma pharmacokinetics and milk
elimination of flunixin (FLU) and 5-hydroxy flunixin (5OH) differ following intramuscular and …