A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms

Q Wu, H Yan, Z Kang - The American Journal of Chinese Medicine, 2024 - World Scientific
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer.
Conventional treatment options for TNBC often have limited efficacy and significant side …

A study of the role of androgen receptor and androgen receptor variant 7 in TNBC patients and the effect of their targeting by Enzalutamide and EPI-001 in MDA-MB …

BM Ali, HS El-Abhar, G Mohamed, HR Nassar… - The Journal of Steroid …, 2025 - Elsevier
The lack of targeted therapy for triple-negative breast cancer (TNBC) is among the
mainsprings of its poor prognosis. This study aimed to elucidate the role of the androgen …

Pioneering first-in-class HDAC-ROCK inhibitors as potential multitarget anticancer agents

M Beljkas, D Ruzic, A Djuric, A Vuletic… - Future Medicinal …, 2025 - Taylor & Francis
Aim With the aim of simultaneously modulating the epigenetic system and the protein kinase
pathway, we selected the enzyme histone deacetylase (HDAC) and the Rho-associated …

Triptolide's Impact on ACER1 Signaling: Inducing Autophagy for Triple-Negative Breast Cancer Suppression

L Huang, R Xue, M Zhu, S Xu, Y Luo, C Qin… - … -Research and Practice, 2025 - Elsevier
Given the absence of estrogen receptor (ER), progesterone receptor (PR), and human
epidermal growth factor receptor-2 (Her-2) in triple-negative breast cancer (TNBC) cells, the …