An underlying question for virtually all single-cell RNA sequencing experiments is how to allocate the limited sequencing budget: deep sequencing of a few cells or shallow …
Diversity indices are useful single-number metrics for characterizing a complex distribution of a set of attributes across a population of interest. The utility of these different metrics or …
M Hassanaly, V Raman - Progress in Energy and Combustion Science, 2021 - Elsevier
In the design of practical combustion systems, ensuring safety and reliability is an important requirement. For instance, reliably avoiding lean blowout, flame flashback or inlet unstart is …
We show that a class of statistical properties of distributions, which includes such practically relevant properties as entropy, the number of distinct elements, and distance metrics …
Y Wu, P Yang - The Annals of Statistics, 2019 - JSTOR
We consider the problem of estimating the support size of a discrete distribution whose minimum nonzero mass is at least 1 k. Under the independent sampling model, we show …
J Jiao, Y Han, T Weissman - IEEE Transactions on Information …, 2018 - ieeexplore.ieee.org
We consider the problem of estimating the L 1 distance between two discrete probability measures P and Q from empirical data in a nonasymptotic and large alphabet setting. When …
J Jiao, K Venkat, Y Han… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
We consider the problem of estimating functionals of discrete distributions, and focus on a tight (up to universal multiplicative constants for each specific functional) nonasymptotic …
Generative probabilistic models of biological sequences have widespread existing and potential applications in analyzing, predicting and designing proteins, RNA and genomes …
BAM Bouwman, F Agostini, S Garnerone, G Petrosino… - Nature protocols, 2020 - nature.com
Abstract sBLISS (in-suspension breaks labeling in situ and sequencing) is a versatile and widely applicable method for identification of endogenous and induced DNA double-strand …