The accumulation of subconcussive impacts on cognitive, imaging, and biomarker outcomes in child and college-aged athletes: a systematic review

AE Walter, JR Wilkes, PA Arnett, SJ Miller… - Brain imaging and …, 2022 - Springer
Examine the effect of subconcussive impact accumulation on cognitive/functional, imaging,
and biomarker outcomes over the course of a single season, specifically in contact sport …

[HTML][HTML] Evaluating glial and neuronal blood biomarkers GFAP and UCH-L1 as gradients of brain injury in concussive, subconcussive and non-concussive trauma: a …

L Papa, MR Zonfrillo, RD Welch, LM Lewis… - BMJ paediatrics …, 2019 - ncbi.nlm.nih.gov
Objectives To evaluate the ability of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase (UCH-L1) to detect concussion in children and adult trauma patients with …

Mitigating the consequences of subconcussive head injuries

EA Nauman, TM Talavage… - Annual review of …, 2020 - annualreviews.org
Subconcussive head injury represents a pathophysiology that spans the expertise of both
clinical neurology and biomechanical engineering. From both viewpoints, the terms injury …

Resting-state fMRI metrics in acute sport-related concussion and their association with clinical recovery: a study from the NCAA-DOD CARE consortium

TB Meier, M Giraldo-Chica, LY España… - Journal of …, 2020 - liebertpub.com
There has been a recent call for longitudinal cohort studies to track the physiological
recovery of sport-related concussion (SRC) and its relationship with clinical recovery …

Dependence on subconcussive impacts of brain metabolism in collision sport athletes: an MR spectroscopic study

S Bari, DO Svaldi, I Jang, TE Shenk, VN Poole… - Brain Imaging and …, 2019 - Springer
Long term neurological impairments due to repetitive head trauma are a growing concern for
collision sport athletes. American Football has the highest rate of reported concussions …

Elevations in microRNA biomarkers in serum are associated with measures of concussion, neurocognitive function, and subconcussive trauma over a single national …

L Papa, SM Slobounov, HC Breiter, A Walter… - Journal of …, 2019 - liebertpub.com
This prospective controlled observational cohort study assessed the performance of a novel
panel of serum microRNA (miRNA) biomarkers on indicators of concussion, subconcussive …

Neuro-ophthalmologic response to repetitive subconcussive head impacts: a randomized clinical trial

MK Nowak, ZW Bevilacqua, K Ejima… - JAMA …, 2020 - jamanetwork.com
Importance Subconcussive head impacts have emerged as a complex public health
concern. The oculomotor system is sensitive to brain trauma; however, neuro …

Repetitive subconcussion results in disrupted neural activity independent of concussion history

KG Solar, M Ventresca, R Zamyadi, J Zhang… - Brain …, 2024 - academic.oup.com
Concussion is a public health crisis that results in a complex cascade of neurochemical
changes that can have life-changing consequences. Subconcussions are generally …

Longitudinal changes in resting state fMRI brain self-similarity of asymptomatic high school American football athletes

B Fitzgerald, S Bari, N Vike, TA Lee, RJ Lycke… - Scientific Reports, 2024 - nature.com
American football has become the focus of numerous studies highlighting a growing
concern that cumulative exposure to repetitive, sports-related head acceleration events …

Association of increased serum S100B levels with high school football subconcussive head impacts

SW Zonner, K Ejima, ZW Bevilacqua… - Frontiers in …, 2019 - frontiersin.org
Astrocyte-enriched marker, S100B, shows promise for gauging the severity of acute brain
trauma, and understanding subconcussive effects will advance its utility in tracking real-time …