Theoretical variance analysis of single-and dual-energy computed tomography methods for calculating proton stopping power ratios of biological tissues

M Yang, G Virshup, J Clayton, XR Zhu… - Physics in Medicine …, 2010 - iopscience.iop.org
We discovered an empirical relationship between the logarithm of mean excitation energy
(ln I m) and the effective atomic number (EAN) of human tissues, which allows for computing …

On the molecular relationship between Hounsfield Unit (HU), mass density, and electron density in computed tomography (CT)

A Sudhyadhom - PLoS One, 2020 - journals.plos.org
Accurate determination of physical/mass and electron densities are critical to accurate
spatial and dosimetric delivery of radiotherapy for photon and charged particles. In this …

Generation of synthetic megavoltage CT for MRI‐only radiotherapy treatment planning using a 3D deep convolutional neural network

JE Scholey, A Rajagopal, EG Vasquez… - Medical …, 2022 - Wiley Online Library
Background Megavoltage computed tomography (MVCT) has been implemented on many
radiotherapy treatment machines for on‐board anatomical visualization, localization, and …

Calibration of CT Hounsfield units for proton therapy treatment planning: use of kilovoltage and megavoltage images and comparison of parameterized methods

L De Marzi, C Lesven, R Ferrand, J Sage… - Physics in Medicine …, 2013 - iopscience.iop.org
Proton beam range is of major concern, in particular, when images used for dose
computations are artifacted (for example in patients with surgically treated bone tumors). We …

Does kV–MV dual-energy computed tomography have an advantage in determining proton stopping power ratios in patients?

M Yang, G Virshup, J Clayton, XR Zhu… - Physics in Medicine …, 2011 - iopscience.iop.org
Conventional kilovoltage (kV) x-ray-based dual-energy CT (DECT) imaging using two
different x-ray energy spectra is sensitive to image noise and beam hardening effects. The …

Construction and verification of a physical chest phantom from suitable tissue equivalent materials for computed tomography examinations

I Amini, P Akhlaghi, P Sarbakhsh - Radiation Physics and Chemistry, 2018 - Elsevier
Physical phantoms are used to optimize various imaging modalities (eg computed
tomography) in terms of X-ray image quality and absorbed dose. In this regard, this study …

Improved accuracy of relative electron density and proton stopping power ratio through CycleGAN machine learning

J Scholey, L Vinas, V Kearney, S Yom… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Kilovoltage computed tomography (kVCT) is the cornerstone of radiotherapy
treatment planning for delineating tissues and towards dose calculation. For the former …

Application of single-and dual-energy CT brain tissue segmentation to PET monitoring of proton therapy

B Berndt, G Landry, F Schwarz… - Physics in Medicine …, 2017 - iopscience.iop.org
The purpose of this work was to evaluate the ability of single and dual energy computed
tomography (SECT, DECT) to estimate tissue composition and density for usage in Monte …

Material elemental decomposition in dual and multi‐energy CT via a sparsity‐dictionary approach for proton stopping power ratio calculation

C Shen, B Li, L Chen, M Yang, Y Lou, X Jia - Medical physics, 2018 - Wiley Online Library
Purpose Accurate calculation of proton stopping power ratio (SPR) relative to water is crucial
to proton therapy treatment planning, since SPR affects prediction of beam range. Current …

kV–kV and kV–MV DECT based estimation of proton stopping power ratio–a simulation study

KW Li, D Fujiwara, A Haga, H Liu, LS Geng - Physica Medica, 2021 - Elsevier
Purpose: This study aims to estimate the proton stopping power ratio (SPR) by using 80–120
kV and 120 kV–6 MV dual-energy CT (DECT) in a fully simulation-based approach for …