Extracellular membrane vesicles in the three domains of life and beyond

S Gill, R Catchpole, P Forterre - FEMS microbiology reviews, 2019 - academic.oup.com
Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles

M Colombo, G Raposo, C Théry - Annual review of cell and …, 2014 - annualreviews.org
In the 1980s, exosomes were described as vesicles of endosomal origin secreted from
reticulocytes. Interest increased around these extracellular vesicles, as they appeared to …

Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

W Heusermann, J Hean, D Trojer, E Steib… - Journal of Cell …, 2016 - rupress.org
Exosomes are nanovesicles released by virtually all cells, which act as intercellular
messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes …

Extracellular vesicles shuffling intercellular messages: for good or for bad

AL Cicero, PD Stahl, G Raposo - Current opinion in cell biology, 2015 - Elsevier
The release of extracellular vesicles (EVs) is a highly conserved process exploited by
diverse organisms as a mode of intercellular communication. Vesicles of sizes ranging from …

Extracellular vesicles—connecting kingdoms

E Woith, G Fuhrmann, MF Melzig - International journal of molecular …, 2019 - mdpi.com
It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or
organism, showing their ubiquity in all empires of life. EVs are defined as naturally released …

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

AH Buck, G Coakley, F Simbari, HJ McSorley… - Nature …, 2014 - nature.com
In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that
the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes …

Exosomes and other extracellular vesicles: the new communicators in parasite infections

G Coakley, RM Maizels, AH Buck - Trends in parasitology, 2015 - cell.com
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

Extracellular vesicles from Trypanosoma brucei mediate virulence factor transfer and cause host anemia

AJ Szempruch, SE Sykes, R Kieft, L Dennison… - Cell, 2016 - cell.com
Intercellular communication between parasites and with host cells provides mechanisms for
parasite development, immune evasion, and disease pathology. Bloodstream African …

Extracellular vesicle RNA: a universal mediator of microbial communication?

JA Tsatsaronis, S Franch-Arroyo, U Resch… - Trends in …, 2018 - cell.com
Both extracellular RNAs and extracellular vesicles (EVs) have recently garnered attention as
novel mediators of intercellular communication in eukaryotes and prokaryotes alike. EVs not …