Interventions for the management of dry mouth: topical therapies

S Furness, HV Worthington, G Bryan… - Cochrane Database …, 2011 - cochranelibrary.com
Background Xerostomia (the feeling of dry mouth) is a common symptom especially in older
adults. Causes of dry mouth include medications, autoimmune disease (Sjögren's …

Sjögren syndrome

CP Mavragani, HM Moutsopoulos - Cmaj, 2014 - Can Med Assoc
• Mild chronic renal compromise34 continued association with antibodies against
neuropeptides. 42 Increased rates of neuroticism, psychoticism, obsessiveness …

Topical and systemic medications for the treatment of primary Sjögren's syndrome

M Ramos-Casals, P Brito-Zeron… - Nature Reviews …, 2012 - nature.com
The treatment of primary Sjögren's syndrome (SS) is based principally on the management
of sicca features and systemic manifestations. Sicca manifestations are treated …

Antimicrobial defense systems in saliva

W van't Hof, ECI Veerman, AVN Amerongen… - Saliva: Secretion and …, 2014 - karger.com
The oral cavity is one of the most heavily colonized parts of our body. The warm, nutrient-rich
and moist environment promotes the growth of a diverse microflora. One of the factors …

Salivary hypofunction and xerostomia: diagnosis and treatment

JC Atkinson, M Grisius, W Massey - Dental Clinics, 2005 - dental.theclinics.com
Saliva plays a central role in the maintenance of oral homeostasis. The complex mixture of
proteins, glycoproteins, mucins, and ions helps prevent dental caries, promotes …

Safety and effectiveness of topical dry mouth products containing olive oil, betaine, and xylitol in reducing xerostomia for polypharmacy‐induced dry mouth

JA Ship, JA McCutcheon… - Journal of oral …, 2007 - Wiley Online Library
summary Polypharmacy is a common cause of salivary hypofunction, producing symptoms
of dry mouth or xerostomia, especially among older populations. As the number of older …

Clinical practice guideline for Sjögren's syndrome 2017

T Sumida, N Azuma, M Moriyama… - Modern …, 2018 - academic.oup.com
Objectives: The objective of this study is to develop clinical practice guideline (CPG) for
Sjögren's syndrome (SS) based on recently available clinical and therapeutic evidences …

Pilocarpine and artificial saliva for the treatment of xerostomia and xerophthalmia in sjögren syndrome: a double‐blind randomized controlled trial

M Cifuentes, P Del Barrio‐Díaz… - British Journal of …, 2018 - academic.oup.com
Background Sjögren syndrome (SS) is associated with xerostomia and xerophthalmia.
Pilocarpine has been shown to stimulate the secretion of saliva. Objectives To investigate …

Evaluation of the clinical efficacy of a mouthwash and oral gel containing the antimicrobial proteins lactoperoxidase, lysozyme and lactoferrin in elderly patients with …

JA Gil‐Montoya, I Guardia‐López… - …, 2008 - Wiley Online Library
Objectives: To evaluate the clinical efficacy of a mouthwash and oral gel containing the
antimicrobial proteins lactoperoxidase, lactoferrin and lysozyme, in a sample of elderly …

Contribution of HIV infection, AIDS, and antiretroviral therapy to exocrine pathogenesis in salivary and lacrimal glands

I Nizamuddin, P Koulen, CP McArthur - International Journal of Molecular …, 2018 - mdpi.com
The structure and function of exocrine glands are negatively affected by human
immunodeficiency virus (HIV) infection and its co-morbidities, including innate and adaptive …