Meta‐analysis: persistence of advanced therapies in the treatment of inflammatory bowel disease

TH Yiu, Y Ko, A Pudipeddi, P Natale… - Alimentary …, 2024 - Wiley Online Library
Background The expanding options in advanced therapies for ulcerative colitis (UC) and
Crohn's disease (CD) present challenges in treatment selection. Persistence analysis …

Risk of Infection in Patients With Inflammatory Bowel Disease Treated With Interleukin-Targeting Agents: A Systematic Review and Meta-Analysis

K Ouranos, H Saleem, S Vassilopoulos… - Inflammatory Bowel …, 2024 - academic.oup.com
Background Patients with inflammatory bowel disease (IBD) are at increased risk of
infection. The aim of this study was to assess the cumulative incidence and risk of infection …

Treatment persistence among bio-naïve patients with Crohn's disease initiated on ustekinumab or adalimumab

M Zhdanava, Z Ding, AM Manceur… - Current Medical …, 2023 - Taylor & Francis
Objectives To compare persistence and describe dose titration among bio-naïve patients
with Crohn's disease (CD) initiated on ustekinumab or adalimumab. Methods Bio-naïve …

[HTML][HTML] Using real-world evidence data and digital monitoring to analyze the hepatotoxic profiles of biologics across more than two million patients

P Banerjee, S Preissner, R Preissner - Scientific Reports, 2023 - nature.com
The real-world evidence data from multiple sources which includes information on patient
health status and medical behavior in routine clinical setup can give deeper insights into …

[HTML][HTML] Ustekinumab in the Treatment of Inflammatory Bowel Diseases: Evolving Paradigms

G Mocci, A Tursi, FM Onidi, P Usai-Satta… - Journal of Clinical …, 2024 - mdpi.com
Inflammatory bowel diseases, comprising Crohn's disease (CD) and ulcerative colitis (UC),
are chronic, relapsing, and remitting immune-mediated inflammatory diseases affecting the …

Clinical use of biologics for Crohn's disease in adults: lessons learned from real-world studies

A Tursi, G Mocci, A Del Gaudio… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction The therapeutic armamentarium for managing Crohn's disease (CD) has
expanded significantly in recent decades. Several biologics with three different mechanisms …

[HTML][HTML] Network meta-analysis on efficacy and safety of different biologics for ulcerative colitis

X Chu, Y Biao, C Liu, Y Zhang, C Liu, J Ma, Y Guo… - BMC …, 2023 - Springer
Background Therapeutic options for ulcerative colitis (UC) have increased since the
introduction of biologics a few decades ago. Due to the wide range of biologics available …

Long-term persistence and other treatment patterns among bio-naïve patients with Crohn's disease treated with ustekinumab or adalimumab

M Zhdanava, Z Ding, AM Manceur, R Zhao… - Current Medical …, 2023 - Taylor & Francis
Objective To estimate long-term persistence among bio-naïve patients with CD initiated on
ustekinumab or adalimumab. Methods Adults with CD initiating ustekinumab or adalimumab …

[PDF][PDF] Comparison of Effectiveness and Safety of Ustekinumab and Adalimumab As Induction or Maintenance Therapy in Patients With Moderate to Severe Crohn's …

VSH Chenna, TK Nagi, ZK Suarez, OL Hernandez… - Cureus, 2023 - cureus.com
This meta-analysis has been conducted to compare ustekinumab and adalimumab as
induction or maintenance therapy in patients with moderate to severe Crohn's disease (CD) …