Role of dopamine in the motivational and cognitive control of behavior
R Cools - The Neuroscientist, 2008 - journals.sagepub.com
Brain dopamine has often been implicated in impulsive and/or inflexible behaviors, which
may reflect failures of motivational and/or cognitive control. However, the precise role of …
may reflect failures of motivational and/or cognitive control. However, the precise role of …
The neurobiology of human aggressive behavior: neuroimaging, genetic, and neurochemical aspects
FA Cupaioli, FA Zucca, C Caporale, KP Lesch… - Progress in neuro …, 2021 - Elsevier
In modern societies, there is a strive to improve the quality of life related to risk of crimes
which inevitably requires a better understanding of brain determinants and mediators of …
which inevitably requires a better understanding of brain determinants and mediators of …
Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis
Genetic variation in catechol-O-methyltransferase (COMT), encoding an enzyme critical for
prefrontal dopamine flux, has been studied extensively using both behavioral and …
prefrontal dopamine flux, has been studied extensively using both behavioral and …
Variation in dopamine genes influences responsivity of the human reward system
JC Dreher, P Kohn, B Kolachana… - Proceedings of the …, 2009 - National Acad Sciences
In humans, dopamine neurotransmission is influenced by functional polymorphisms in the
dopamine transporter (DAT 1) and catechol-O-methyltransferase (COMT) genes. Here, we …
dopamine transporter (DAT 1) and catechol-O-methyltransferase (COMT) genes. Here, we …
Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism
JH Barnett, L Scoriels, MR Munafò - Biological psychiatry, 2008 - Elsevier
BACKGROUND: Cognitive endophenotypes may further our understanding of the genetic
basis of psychiatric disorders, and the catechol-O-methyltransferase (COMT) gene is a …
basis of psychiatric disorders, and the catechol-O-methyltransferase (COMT) gene is a …
Effects of COMT polymorphisms on brain function and behavior in health and disease
AV Witte, A Flöel - Brain research bulletin, 2012 - Elsevier
The catechol-O-methyltransferase (COMT) gene has attracted strong neuroscientific interest
due to its implication in dopaminergic neurotransmission. One of its most widely studied …
due to its implication in dopaminergic neurotransmission. One of its most widely studied …
The role of prefrontal catecholamines in attention and working memory
KL Clark, B Noudoost - Frontiers in neural circuits, 2014 - frontiersin.org
While much progress has been made in identifying the brain regions and neurochemical
systems involved in the cognitive processes disrupted in mental illnesses, to date, the level …
systems involved in the cognitive processes disrupted in mental illnesses, to date, the level …
A neural network model of individual differences in task switching abilities
We use a biologically grounded neural network model to investigate the brain mechanisms
underlying individual differences specific to the selection and instantiation of representations …
underlying individual differences specific to the selection and instantiation of representations …
Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension.
Several single nucleotide polymorphisms have been linked to neural and cognitive variation
in healthy adults. We examined contribution of three polymorphisms frequently associated …
in healthy adults. We examined contribution of three polymorphisms frequently associated …
The flexible mind is associated with the catechol-O-methyltransferase (COMT) Val158Met polymorphism: evidence for a role of dopamine in the control of task …
Genetic variability related to the catechol-O-methyltransferase (COMT) gene (Val158Met
polymorphism) has received increasing attention as a possible modulator of cognitive …
polymorphism) has received increasing attention as a possible modulator of cognitive …