Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of
glucose and metabolites activates resident macrophages in kidneys. Resident macrophages …

Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …

Pyroptosis, known as one typical mode of programmed cell death, is generally characterized
by the cleaved gasdermin family (GSDMs) forming pores in the cell membrane and inducing …

Introduction The immunosuppressive capacity of mesenchymal stem cells (MSCs) is
dependent on the “license” of several pro-inflammatory factors to express …

Chronic kidney disease (CKD) is a growing health concern with a complex etiological
landscape. Among the numerous factors implicated, vitamin D binding protein (VDBP) has …

Diabetic kidney disease (DKD) is a major microvascular complication of diabetes, and
hyperglycemic memory associated with diabetes carries the risk of disease occurrence …

N6-methyladensine (m6A) has been identified as the best-characterized and the most
abundant mRNA modification in eukaryotes. It can be dynamically regulated, removed, and …

Objective To systematically evaluate the correlation between urinary vitamin D-binding
protein (VDBP) and diabetic kidney disease and to evaluate the relationship between …

Background: Ischemic stroke (IS) is a highly heterogeneous disease. Recent studies have
shown that epigenetic variables affect the immune response. However, only a few studies …

The intricate crosstalk between long noncoding RNAs (lncRNAs) and epigenetic
modifications such as chromatin/histone methylation and acetylation offer new perspectives …