Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Uptake and efflux transporters determine plasma and tissue concentrations of a broad
variety of drugs. They are localized in organs such as small intestine, liver, and kidney …

Synergy is a process in which some substances cooperate to reach a combined effect that is
greater than the sum of their separate effects. It can be considered a natural “straight” …

Herbal medicine, especially traditional Chinese medicine and Ayurvedic medicine have
played and still play an important role in fighting against various diseases. Emerging clinical …

Neurodegenerative disorders (NDDs) such as Alzheimer's and Parkinson's diseases are the
most common age-related pathologies that affect millions of people all over the world. To …

This review highlights using nanotechnology in increasing the bioavailability of AP
(Apigenin) to enhance its therapeutic efficacy in breast cancer treatment. Breast cancer is …

Organic anion-transporting polypeptides or OATPs are central transporters in the disposition
of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …

In recent years, an increasing number of clinical drug–drug interactions (DDIs) have been
attributed to inhibition of intestinal organic anion-transporting polypeptides (OATPs); …

Food–drug interaction studies are critical to evaluate appropriate dosing, timing, and
formulation of new drug candidates. These interactions often reflect prandial-associated …

This study aimed to evaluate the effects of green tea on the pharmacokinetics and
pharmacodynamics of the β‐blocker nadolol. Ten healthy volunteers received a single oral …