EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Human and ecological risk assessment of a crop protection chemical: a case study with the azole fungicide epoxiconazole

JE Chambers, H Greim, RJ Kendall… - Critical reviews in …, 2014 - Taylor & Francis
Conventional risk assessments for crop protection chemicals compare the potential for
causing toxicity (hazard identification) to anticipated exposure. New regulatory approaches …

Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2015 - Wiley Online Library
This opinion describes the assessment of the risks to public health associated with
bisphenol A (BPA) exposure. Exposure was assessed for various groups of the human …

Bisphenol A exposure during adulthood causes augmentation of follicular atresia and luteal regression by decreasing 17β-estradiol synthesis via downregulation of …

SG Lee, JY Kim, JY Chung, YJ Kim… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: Bisphenol A (BPA) has been detected in human body fluids, such as serum
and ovarian follicular fluids. Several reports indicated that BPA exposure is associated with …

Comparative toxicity, oxidative stress and endocrine disruption potential of plasticizers in JEG-3 human placental cells

E Pérez-Albaladejo, D Fernandes, S Lacorte, C Porte - Toxicology in Vitro, 2017 - Elsevier
Plasticizers are suspected to be toxic and/or to modulate or disrupt the endocrine system of
humans and to cross the placental barrier, being embryonic and fetal development a …

[HTML][HTML] Concentration Addition, Independent Action and Generalized Concentration Addition Models for Mixture Effect Prediction of Sex Hormone Synthesis In Vitro

N Hadrup, C Taxvig, M Pedersen, C Nellemann… - PloS one, 2013 - journals.plos.org
Humans are concomitantly exposed to numerous chemicals. An infinite number of
combinations and doses thereof can be imagined. For toxicological risk assessment the …

[PDF][PDF] International regulatory needs for development of an IATA for non-genotoxic carcinogenic chemical substances

MN Jacobs, A Colacci, K Louekari, M Luijten… - …, 2016 - pdfs.semanticscholar.org
Although regulatory requirements for carcinogenicity testing of chemicals vary according to
product sector and regulatory jurisdiction, the standard approach starts with a battery of …

The effect of aromatase on the reproductive function of obese males

X Xu, M Sun, J Ye, D Luo, X Su, D Zheng… - Hormone and …, 2017 - thieme-connect.com
Obesity has increased dramatically worldwide, which is associated with male infertility.
Androgen deficiency, impaired spermatogenesis, and erectile dysfunction are characteristics …

Atrazine impairs testicular function in BalB/c mice by affecting Leydig cells

SO Abarikwu, GMJ Costa, SMSN Lacerda… - Toxicology, 2021 - Elsevier
Several studies have reported the effects of atrazine on the gonads of many experimental
models. However, the short-term effects of in vivo exposure to atrazine on the testes of mice …

Effects of some endocrine disruptors on cell cycle progression and murine dendritic cell differentiation

L Pisapia, G Del Pozzo, P Barba, L Caputo… - General and …, 2012 - Elsevier
Endocrine disruptor chemicals (EDCs), which are predominantly present in the environment,
are able to mimic or antagonise the biological activity of hormones primarily through the …