Critical COVID-19 patients admitted to the intensive care unit (ICU) frequently suffer from
severe multiple organ dysfunction with underlying widespread cell death. Ferroptosis and …

The pandemic of the coronavirus disease (COVID-19) caused by SARS-CoV-2 affects
millions of people worldwide. There are still many unknown aspects to this infection which …

Rationale: Capillary leakage frequently occurs during sepsis and after major surgery and is
associated with microvascular dysfunction and adverse outcome. Procalcitonin is a well …

Recent years have seen a resurgence of interest for the renin–angiotensin–aldosterone
system in critically ill patients. Emerging data suggest that this vital homeostatic system …

Aim Concerns have been raised that dipeptidyl‐peptidase 4 inhibitors (DPP‐4i) may
increase the risk of pneumonia. We analysed observational data and clinical trials to explore …

Sepsis and septic shock are global healthcare problems associated with high mortality rates.
Activation of the renin-angiotensin-aldosterone system (RAAS) is an early event in sepsis …

Sepsis is a fatal organ dysfunction characterized by the simultaneous hyperinflammation
and immunosuppression. Nowadays, the early precision intervention of sepsis is …

Background. Septic shock is a common clinical critical disease with high mortality,
hemodynamic instability, and easy to be complicated with multiple organ failure. The rapid …

Prolyl carboxypeptidase (PRCP) is involved in metabolic disorders by hydrolyzing
anorexigenic peptides. A link between serum PRCP activity and obesity has been reported …

Background COVID-19 patients experience several features of dysregulated immune system
observed in sepsis. We previously showed a dysregulation of several proline-selective …