Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Depressive and manic phases in bipolar disorder show opposite constellations of affective,
cognitive, and psychomotor symptoms. At a neural level, these may be related to …

Abstract The Research Domain Criteria (RDoC) adopts a dimensional approach for
examining pathophysiological processes underlying categorically defined psychiatric …

Objectives Bipolar disorder (BD) has been associated with dysfunctional brain connectivity
and with family chaos. It is not known whether aberrant connectivity occurs before illness …

Resting state functional magnetic imaging (fMRI) is a novel means to examine functional
brain networks. It allows investigators to identify functional networks defined by distinct …

It remains unclear the degree to which youths with episodic mania (bipolar disorder; BD) vs.
those with chronic, severe irritability (severe mood dysregulation, SMD) should be placed in …

Mood disorders/psychosis have been associated with dysfunctions in the default mode
network (DMN). However, the relative contributions of DMN regions to state and trait …

Background: The insula is instrumental in integrating the emotional, cognitive, and sensory-
motor systems. This manuscript lays a foundational framework for understanding the insula's …

BackgroundMajor questions remain regarding the dysfunctional neural circuitry underlying
the pathophysiology of bipolar disorder (BD) in both youths and adults. In both age groups …

Objective This study used independent component analysis (ICA) to investigate the
connectivity patterns of resting-state functional large-scale brain networks in patients with …