Mitochondria as multifaceted regulators of cell death

FJ Bock, SWG Tait - Nature reviews Molecular cell biology, 2020 - nature.com
Through their many and varied metabolic functions, mitochondria power life. Paradoxically,
mitochondria also have a central role in apoptotic cell death. Upon induction of …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

A cell's fate: an overview of the molecular biology and genetics of apoptosis

GC Cavalcante, AP Schaan, GF Cabral… - International journal of …, 2019 - mdpi.com
Apoptosis is one of the main types of regulated cell death, a complex process that can be
triggered by external or internal stimuli, which activate the extrinsic or the intrinsic pathway …

New insights into apoptosome structure and function

L Dorstyn, CW Akey, S Kumar - Cell Death & Differentiation, 2018 - nature.com
The apoptosome is a platform that activates apical procaspases in response to intrinsic cell
death signals. Biochemical and structural studies in the past two decades have extended …

Enhancing Apoptosome Assembly via Mito‐Biomimetic Lipid Nanocarrier for Cancer Therapy

H Han, J Chen, J Li, A Correia, R Bártolo… - Advanced Functional …, 2023 - Wiley Online Library
Apoptosis is the natural programmed cell death process, which is responsible for abnormal
cell clearance. However, many cancer cells develop various mechanisms to escape …

Polysaccharides of mushroom Pleurotus spp.: New extraction techniques, biological activities and development of new technologies

JR Barbosa, MM dos Santos Freitas… - Carbohydrate …, 2020 - Elsevier
The biodiversity of mushrooms Pleurotus spp. is impressive due to its complexity and
diversity related to the composition of chemical structures such as polysaccharides …

Anoikis resistance––protagonists of breast cancer cells survive and metastasize after ECM detachment

Y Dai, X Zhang, Y Ou, L Zou, D Zhang, Q Yang… - Cell Communication and …, 2023 - Springer
Breast cancer exhibits the highest global incidence among all tumor types. Regardless of
the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of …

Multienzymatic antioxidant activity of manganese-based nanoparticles for protection against oxidative cell damage

Y Zhang, L Chen, R Sun, R Lv, T Du, Y Li… - ACS Biomaterials …, 2022 - ACS Publications
Oxidative stress is related to many diseases, but available clinical treatment methods are
currently limited. Exploitation of enzyme-mimicking nanomaterials (nanozymes) is a …

Human papillomavirus infection, cervical cancer and the less explored role of trace elements

AB Sravani, V Ghate, S Lewis - Biological Trace Element Research, 2023 - Springer
Cervical cancer is an aggressive type of cancer affecting women worldwide. Many affected
individuals rely on smear tests for the diagnosis, surgery, chemotherapy, or radiation for their …

Apoptotic signaling: Beyond cell death

M Nano, DJ Montell - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Apoptosis is the best described form of regulated cell death, and was, until relatively
recently, considered irreversible once particular biochemical points-of-no-return were …