[HTML][HTML] The role of m6A RNA methylation in cancer metabolism
Y An, H Duan - Molecular cancer, 2022 - Springer
Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …
LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer
YT Tan, JF Lin, T Li, JJ Li, RH Xu… - Cancer …, 2021 - Wiley Online Library
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …
has historically been considered a general phenomenon of tumors. It is well recognized that …
[HTML][HTML] Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression
H Liu, D Li, L Sun, H Qin, A Fan, L Meng… - Molecular cancer, 2022 - Springer
Background Epithelial-to-mesenchymal transition (EMT) is a process linked to metastasis
and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously …
and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously …
[HTML][HTML] Mechanism of RNA modification N6-methyladenosine in human cancer
Z Zhou, J Lv, H Yu, J Han, X Yang, D Feng, Q Wu… - Molecular cancer, 2020 - Springer
Since the breakthrough discoveries of DNA and histone modifications, the field of RNA
modifications has gained increasing interest in the scientific community. The discovery of N6 …
modifications has gained increasing interest in the scientific community. The discovery of N6 …
[HTML][HTML] Novel insights into the interplay between m6A modification and noncoding RNAs in cancer
YC Yi, XY Chen, J Zhang, JS Zhu - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
Long non-coding RNAs in the doxorubicin resistance of cancer cells
S Ashrafizaveh, M Ashrafizadeh, A Zarrabi… - Cancer Letters, 2021 - Elsevier
Chemotherapy is the main treatment used for cancer patients failing surgery. Doxorubicin
(DOX) is a well-known chemotherapeutic agent capable of suppressing proliferation in …
(DOX) is a well-known chemotherapeutic agent capable of suppressing proliferation in …
[HTML][HTML] LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma
Y Liu, M Shi, X He, Y Cao, P Liu, F Li, S Zou… - Journal of Hematology & …, 2022 - Springer
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated
macrophages (TAMs). In this study, we found the function and molecular mechanism of …
macrophages (TAMs). In this study, we found the function and molecular mechanism of …
[HTML][HTML] FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis
DY Ruan, T Li, YN Wang, Q Meng, Y Li, K Yu, M Wang… - Oncogene, 2021 - nature.com
Fat mass and obesity-associated protein (FTO), an N6-methyladenosine (m6A)
demethylase, participates in tumor progression and metastasis in many malignancies, but its …
demethylase, participates in tumor progression and metastasis in many malignancies, but its …
[HTML][HTML] CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA
B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …
and progression of human malignancies, but the underlying mechanisms remain largely …
[HTML][HTML] The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers
J Wang, L Chen, P Qiang - Cancer cell international, 2021 - Springer
The human insulin-like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2/IMP2) is
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …