Inflammatory processes and microglia activation accompany most of the pathophysiological
diseases in the central nervous system. It is proven that glial pathology precedes and even …

More than half a century has passed since the introduction of the National Filariasis Control
Program; however, as of 2023, lymphatic filariasis (LF) still prevails globally, particularly in …

Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease leading to
continuous mucosal inflammation in the rectum extending proximally towards the colon …

Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …

Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …

The filarial worms of Wuchereria bancrofti are the primary cause of lymphatic filariasis (LF), a
mosquito-borne disease among the neglected tropical parasitic diseases. Considering the …

Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the
proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 …

Macrophages are integral part of the body's defense against pathogens and serve as vital
regulators of inflammation. Adaptor molecules, featuring diverse domains, intricately …

Background. Lymphatic filariasis, frequently caused from Wuchereria bancrofti infection, is
endemic in several parts of the globe and responsible for human health problems and …

Purpose. To investigate the expression profiles of long noncoding RNAs (lncRNAs) in
patients with atrial fibrillation (AF). Methods. The peripheral blood monocytes of a total of 20 …