Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …

Epoxyeicosatrienoic acids (EETs), which function primarily as autocrine and paracrine
mediators in the cardiovascular and renal systems, are synthesized from arachidonic acid by …

Triclosan (2, 4, 4′-trichloro-2′-hydroxy-diphenyl ether) is an antibacterial compound that
has been used in consumer products for about 40 years. The tolerability and safety of …

Disturbed lipid metabolism precedes alcoholic liver injury. Whether and how AhR alters
degradation of lipids, particularly phospho-/sphingo-lipids during alcohol exposure, was not …

Perfluoroalkyl acids (PFAAs) are perfluorinated compounds that widely exist in the
environment and can elicit adverse effects including endocrine disruption in humans and …

Due to the aging population in the world, neurodegenerative diseases have become a
serious public health issue that greatly impacts patients' quality of life and adds a huge …

Toxicologic and physiologic roles of CYP1A enzyme induction, the major biochemical effect
of aryl hydrocarbon receptor activation by TCDD and other receptor ligands, are unknown …

Drawing on all data available in 2003, the WoE of the human epidemiological data for
polychlorinated biphenyls (PCBs) demonstrates that exposure to a mixture of PCBs (ie …

Polar cod (Boreogadus saida) has been used as a model Arctic species for hazard
assessment of environmental stressors such as polycyclic aromatic hydrocarbons (PAHs) …

Previous reports have proposed a cross-talk between the nuclear factor erythroid-2 p45-
related factor-2 (Nrf2)/antioxidant response element (ARE) and the aryl hydrocarbon …