Metal homeostasis in the central nervous system (CNS) is a crucial component of healthy
brain function, because metals serve as enzymatic cofactors and are key components of …

Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Aluminium (Al) is clearly a powerful neurotoxicant. Considerable evidence exists that Al may
play a role in the aetiology or pathogenesis of Alzheimer's disease (AD), but whether the link …

Amyloid β (Aβ) is a main component of senile plaques in Alzheimer's disease and induces
neuronal cell death. Reactive oxygen species (ROS), nitric oxide and endoplasmic reticulum …

Glutamine is a multifaceted amino acid used for hepatic urea synthesis, renal
ammoniagenesis, gluconeogenesis in both liver and kidney, and as a major respiratory fuel …

Despite elegant research involving molecular biology studies and determination of the
genetic mechanisms of aging, practical information on how to forestall or reverse the …

Aluminium, an environmentally abundant non-redox trivalent cation has long been
implicated in the pathogenesis of Alzheimer's disease (AD). However, the definite …

A central role of iron in the pathogenesis of Parkinson's disease (PD), due to its increase in
substantia nigra pars compacta dopaminergic neurons and reactive microglia and its …

Aging leads to functional changes in the hippocampus, and consequently induces cognitive
deficits, such as failure of memory. Neurogenesis in the hippocampal dentate gyrus …

Aluminum is a ubiquitously abundant nonessential element. Aluminum has been associated
with neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral …