SOX transcription factors as important regulators of neuronal and glial differentiation during nervous system development and adult neurogenesis
M Stevanovic, D Drakulic, A Lazic… - Frontiers in molecular …, 2021 - frontiersin.org
The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …
properties of both classical TFs and architectural components of chromatin. Since the …
Interactions between SOX factors and Wnt/β‐catenin signaling in development and disease
The SOX family of transcription factors have emerged as modulators of canonical Wnt/β‐
catenin signaling in diverse development and disease contexts. There are over 20 SOX …
catenin signaling in diverse development and disease contexts. There are over 20 SOX …
[HTML][HTML] SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
The Y chromosome gene Sry encodes a transcription factor required to initiate testis
development. The related autosomal gene Sox9 is up-regulated shortly after the onset of Sry …
development. The related autosomal gene Sox9 is up-regulated shortly after the onset of Sry …
Regulation of nuclear transport: central role in development and transformation?
Transport of macromolecules into and out of the nucleus is generally effected by targeting
signals that are recognized by specific members of the importin/exportin transport receptor …
signals that are recognized by specific members of the importin/exportin transport receptor …
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators
SOX transcription factors perform a remarkable variety of important roles in vertebrate
development, either activating or repressing specific target genes through interaction with …
development, either activating or repressing specific target genes through interaction with …
The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group …
VR Harley, MJ Clarkson, A Argentaro - Endocrine reviews, 2003 - academic.oup.com
Despite 12 yr since the discovery of SRY, little is known at the molecular level about how
SRY and the SRY-related protein, SOX9 [SRY-related high-mobility group (HMG) box 9] …
SRY and the SRY-related protein, SOX9 [SRY-related high-mobility group (HMG) box 9] …
Prostaglandin D2 induces nuclear import of the sex‐determining factor SOX9 via its cAMP‐PKA phosphorylation
During mammalian gonadal development, nuclear import/export of the transcription factor
SOX9 is a critical step of the Sry‐initiated testis‐determining cascade. In this study, we …
SOX9 is a critical step of the Sry‐initiated testis‐determining cascade. In this study, we …
Dimerization of SOX9 is required for chondrogenesis, but not for sex determination
P Bernard, P Tang, S Liu, P Dewing… - Human molecular …, 2003 - academic.oup.com
The SRY-related SOX9 gene is involved in both chondrogenesis and the early steps of
mammalian sex determination. Mutations in the human SOX9 gene cause campomelic …
mammalian sex determination. Mutations in the human SOX9 gene cause campomelic …
Diverse regulation but conserved function: SOX9 in vertebrate sex determination
Sex determination occurs early during embryogenesis among vertebrates. It involves the
differentiation of the bipotential gonad to ovaries or testes by a fascinating diversity of …
differentiation of the bipotential gonad to ovaries or testes by a fascinating diversity of …
SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes
T Aigner, PM Gebhard, E Schmid, B Bau, V Harley… - Matrix Biology, 2003 - Elsevier
Anabolic activity is a crucial activity of articular chondrocytes and its failure is one major
reason of osteoarthritic cartilage degeneration. The intracellular factors responsible for the …
reason of osteoarthritic cartilage degeneration. The intracellular factors responsible for the …