Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review

S Bandopadhyay, S Mandal, M Ghorai… - Journal of Cellular …, 2023 - Wiley Online Library
Centella asiatica is an ethnomedicinal herbaceous species that grows abundantly in tropical
and sub‐tropical regions of China, India, South‐Eastern Asia and Africa. It is a popular …

Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer's disease: The role of antioxidants in prevention and …

G Juszczyk, J Mikulska, K Kasperek, D Pietrzak… - Antioxidants, 2021 - mdpi.com
There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …

A Systematic Review of the Effect of Centella asiatica on Wound Healing

E Arribas-López, N Zand, O Ojo, MJ Snowden… - International Journal of …, 2022 - mdpi.com
Background: Under metabolic stress conditions, there is a higher demand for nutrients which
needs to be met. This is to reduce the risk of delay in wound healing which could lead to …

Insights into antioxidant activities and anti-skin-aging potential of callus extract from Centella asiatica (L.)

V Buranasudja, D Rani, A Malla, K Kobtrakul… - Scientific Reports, 2021 - nature.com
Formation of oxidative stress in dermal fibroblasts plays crucial roles in aging processes of
skin. The use of phytochemicals that can promote capacity of fibroblasts to combat oxidative …

Asiaticoside-laden silk nanofiber hydrogels to regulate inflammation and angiogenesis for scarless skin regeneration

L Liu, Z Ding, Y Yang, Z Zhang, Q Lu… - Biomaterials science, 2021 - pubs.rsc.org
Scarless skin regeneration remains a challenge due to the complicated microenvironment
involved in wound healing. Here, the hydrophobic drug, asiaticoside (AC), was loaded …

Natural product-based pharmacological studies for neurological disorders

V Puri, N Kanojia, A Sharma, K Huanbutta… - Frontiers in …, 2022 - frontiersin.org
Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …

Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal …

J Zhao, J Shi, Y Shan, M Yu, X Zhu, Y Zhu, L Liu… - Cellular & Molecular …, 2020 - Springer
Background Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis
(PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an …

Combining in silico and in vitro studies to evaluate the acetylcholinesterase inhibitory profile of different accessions and the biomarker triterpenes of Centella asiatica

NA Jusril, ANN Muhamad Juhari, SI Abu Bakar… - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease and the most cause of dementia
in elderly adults. Acetylcholinesterase (AChE) is an important beneficial target for AD to …

Plant ingredients in Thai food: a well-rounded diet for natural bioactive associated with medicinal properties

R Buathong, S Duangsrisai - PeerJ, 2023 - peerj.com
Background Seeking cures for chronic inflammation-associated diseases and infectious
diseases caused by critical human pathogens is challenging and time-consuming. Even as …

Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered

AB Speers, KM Wright, MS Brandes… - Frontiers in …, 2024 - frontiersin.org
Introduction A water extract of Centella asiatica (L.) Urban [Apiaceae](CAW) has
demonstrated cognitive-enhancing effects in mouse models of Alzheimer's disease and …