[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Technologies and standardization in research on extracellular vesicles

S Gandham, X Su, J Wood, AL Nocera, SC Alli… - Trends in …, 2020 - cell.com
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …

Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin

RE Veerman, L Teeuwen, P Czarnewski… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers,
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …

Role of human milk bioactives on infants' gut and immune health

LE Carr, MD Virmani, F Rosa, D Munblit… - Frontiers in …, 2021 - frontiersin.org
Exclusive human milk feeding of the newborn is recommended during the first 6 months of
life to promote optimal health outcomes during early life and beyond. Human milk contains a …

High-quality milk exosomes as oral drug delivery system

J Zhong, B Xia, S Shan, A Zheng, S Zhang, J Chen… - Biomaterials, 2021 - Elsevier
Many drugs must be administered intravenously instead of oral administration due to their
poor oral bioavailability. The cost of repeated infusion treatment for 6 weeks every year is as …

Human breast milk: from food to active immune response with disease protection in infants and mothers

GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …

Bovine milk-derived exosomes as a drug delivery vehicle for miRNA-based therapy

L del Pozo-Acebo, MC López de las Hazas… - International journal of …, 2021 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with a known role as mediators of gene
expression in crucial biological processes, which converts them into high potential …

[HTML][HTML] Milk exosomes: Nature's abundant nanoplatform for theranostic applications

B Adriano, NM Cotto, N Chauhan, M Jaggi… - Bioactive materials, 2021 - Elsevier
Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are
smaller intracellular membrane nanoparticle vesicles. Exosomes have proven to be …

Milk exosomes with enhanced mucus penetrability for oral delivery of siRNA

MR Warren, C Zhang, A Vedadghavami… - Biomaterials …, 2021 - pubs.rsc.org
Bovine milk-derived exosomes have recently emerged as a promising nano-vehicle for the
encapsulation and delivery of macromolecular biotherapeutics. Here we engineer high …

Exosomes in the diagnosis and treatment of renal cell cancer

S Boussios, P Devo, ICA Goodall, K Sirlantzis… - International journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the most prevalent type of kidney cancer originating from
renal tubular epithelial cells, with clear cell RCC comprising approximately 80% of cases …