The emergence of nanomedicine drugs as a result of the fast advancement of nanotechnology offers enormous potential for improving cancer treatment strategies. The …
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to various cancers. Their efficacy, however, is limited by their low persistence and anergy …
Artificial antigen presenting cells are biomimetic particles that recapitulate the signals presented by natural antigen presenting cells in order to stimulate T cells in an antigen …
F Hou, Z Guo, MT Ho, Y Hui, CX Zhao - ACS nano, 2024 - ACS Publications
T cell-based adoptive cell therapy (ACT) has emerged as a promising treatment for various diseases, particularly cancers. Unlike other immunotherapy modalities, ACT involves directly …
Recent research in artificial cell production holds promise for the development of delivery agents with therapeutic effects akin to real cells. To succeed in these applications, these …
AC Wauters, JF Scheerstra, MMT van Leent… - Nature …, 2024 - nature.com
Regulating innate immunity is an emerging approach to improve cancer immunotherapy. Such regulation requires engaging myeloid cells by delivering immunomodulatory …
Activation of immune cells is an essential process in innate and adaptive immunity. A high number of immune cell activation pathways have been discovered, which are stimulated via …
N Eckman, A Nejatfard, R Cavet… - Nature Reviews …, 2024 - nature.com
Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …
While existing synthetic technologies for ex vivo T-cell activation face challenges like suboptimal expansion rates and low effectiveness, artificial antigen-presenting cells …