Prevalence and health consequences of obesity differ between men and women. Yet, most
preclinical studies investigating the etiology of obesity have, to date, been conducted in …

Unhealthy lifestyles and mental health problems are increasingly prevalent globally. Not
only are 'junk food'-induced overweight and obesity risk factors for the development of brain …

Abstract Background/Objective Female mice are often excluded from diet-induced obesity
studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However …

Accumulating studies suggest that overnutrition-associated obesity may lead to
development of type 2 diabetes mellitus and metabolic syndromes (MetS). MetS and its …

Aging is inevitable and it is one of the major contributors to cognitive decline. However, the
mechanisms underlying age-related cognitive decline are still the object of extensive …

Decreased estrogens during menopause are associated with increased risk of anxiety,
depression, type 2 diabetes and obesity. Similarly, depleting estrogens in rodents by …

Recent evidence has established that consumption of High-fat diet (HFD)-induced obesity is
associated with deficits in hippocampus-dependent memory/learning and mood states …

The biological mechanisms linking diet‐related obesity and autistic behaviors remain
unclear. Metformin has proven to be beneficial in the treatment of many syndromes …

Although several epidemiologic and animal studies have revealed correlations between
obesity and neurodegenerative disorders, such as Parkinson disease (PD), the underlying …

The difficulty of long-term management has produced a high rate of failure for obesity
patients. Therefore, improving the efficacy of current obesity treatment is a significant goal …