According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

Aging of the vasculature is characterized by endothelial dysfunction and arterial stiffening,
two key events in the pathogenesis of cardiovascular disease (CVD). Treatment with sodium …

Aortic stiffness is a hallmark of cardiovascular disease, but its pathophysiology remains
incompletely understood. This study presents an in-dept characterization of aortic aging in …

The negative relationship between testosterone and inflammatory cytokines has been
reported for decades, although the exact mechanisms of their interactions are still not clear …

The endothelial glycocalyx (EG) as part of the endothelial surface layer (ESL) is an important
regulator of vascular function and homeostasis, including permeability, vascular tone …

Purpose High-intensity interval training (HIIT) and blood flow restriction (BFR) training have
been used to enhance athletic performance and cardiovascular health. Combining these …

Background Skeletal muscles are postulated to be a potent regulator of systemic nitric oxide
homeostasis. In this study, we aimed to evaluate the impact of physical training on the heart …

Sustained physical activity induces morphological and functional changes in the
cardiovascular system. While mostly physiological, they can also become a trigger for major …

Professional athletes are often exposed to high training loads that may lead to overfatigue,
overreaching and overtraining that might have a detrimental effects on vascular health. We …