The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

Alcoholism is a complex brain disease characterized by three distinct stages of the addiction
cycle that manifest as neuroadaptive changes in the brain. One such stage of the addiction …

Anxiety disorders are highly prevalent psychiatric disorders often comorbid with depression
and substance abuse. Twin studies have shown that anxiety disorders are moderately …

Environmental factors, including substance abuse and stress, cause long-lasting changes in
the regulation of gene expression in the brain via epigenetic mechanisms, such as DNA …

Positive effects of alcohol drinking such as anxiolysis and euphoria appear to be a crucial
factor in the initiation and maintenance of alcohol use disorder (AUD). However, the …

Adolescence represents a crucial phase of synaptic maturation characterized by molecular
changes in the developing brain that shape normal behavioral patterns. Epigenetic …

Stress exposure is associated with psychiatric conditions, such as depression, anxiety, and
post-traumatic stress disorder (PTSD). It is also a vulnerability factor to developing or …

Noncoding RNAs (ncRNAs) represent the majority of the transcriptome and play important
roles in regulating neuronal functions. ncRNAs are exceptionally diverse in both structure …

Alcohol consumption prompts detrimental psychological, pathophysiological and health
issues, representing one of the major causes of death worldwide. Alcohol use disorder …

Chronic alcohol exposure produces widespread neuroadaptations and alterations in gene
expression in human alcoholics and animal models. Technological advances in the past …