Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Significance: Alzheimer disease (AD) is an all-too-common condition in the aging
population. However, aging does not automatically equal neurodegeneration and memory …

Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …

Pannexin-1 (Panx1) is a large-pore ion and solute permeable channel highly expressed in
the nervous system, where it subserves diverse processes, including neurite outgrowth …

Probenecid is an old uricosuric agent used in clinics to treat gout and reduce the renal
excretion of antibiotics. In recent years, probenecid has gained attention due to its ability to …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
amyloid-β (Aβ) deposits and neurofibrillary tangles. Pterostilbene (PTE), a bioactive …

Purinergic signaling encompasses the cycle of adenosine 5′ triphosphate (ATP) release
and its metabolism into nucleotide and nucleoside derivatives, the direct release of …

Aging is a natural process that includes several changes that gradually make organisms
degenerate and die. Harman's theory proposes that aging is a consequence of the …

Beta-amyloid protein [Aβ (1-42)] plays an important role in the disease progress and
pathophysiology of Alzheimer's disease (AD). Membrane properties and neuronal …

Objectives To examine serum concentrations of neurotensin, pannexin-1 and sestrin-2, and
their correlations with subjective and objective sleep quality and cognitive function in the …