[HTML][HTML] An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

S Bastani, V Vahedian, M Rashidi, A Mir… - Biomedicine & …, 2022 - Elsevier
Crocin, an active ingredient derived from saffron, is one of the herbal components that has
recently been considered by researchers. Crocin has been shown to have many anti …

Active constituents of saffron (Crocus sativus L.) and their prospects in treating neurodegenerative diseases

W Yang, X Qiu, Q Wu, F Chang… - Experimental and …, 2023 - spandidos-publications.com
Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …

Antioxidant therapies for neuroprotection—A review

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Although moderate concentrations of reactive oxygen species (ROS) and reactive nitrogen
species (RNS) are crucial for various physiological processes within the human body, their …

[HTML][HTML] Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda, H Hosseinzadeh - Iranian Journal of Basic Medical …, 2022 - ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …

Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials

Z Long, W Xiang, Q He, W Xiao, H Wei, H Li… - Frontiers in …, 2023 - frontiersin.org
Objective To evaluate safety and efficacy of dietary polyphenols in the treatment of
rheumatoid arthritis (RA). Methods CNKI, Pubmed, Cochrane library, Embase were …

Crocins: A comprehensive review of structural characteristics, pharmacokinetics and therapeutic effects

Y Song, Y Wang, Y Zheng, T Liu, C Zhang - Fitoterapia, 2021 - Elsevier
Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular …

M Scuto, S Modafferi, F Rampulla, V Zimbone… - Mechanisms of Ageing …, 2022 - Elsevier
Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms

M Iranshahy, B Javadi, A Sahebkar - Phytotherapy research, 2022 - Wiley Online Library
Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

Therapeutic potentials of crocin in medication of neurological disorders

S Ahmed, MM Hasan, M Heydari, A Rauf… - Food and Chemical …, 2020 - Elsevier
Neurological sicknesses are serious, multifactorial, debilitating disorders that may cause
neurodegeneration. Neuroprotection is the protection of the structure and capacity of …

Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways

BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …