Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

Biomimetic Nanophotosensitizer amplifies immunogenic pyroptosis and triggers synergistic Cancer Therapy

Q Wang, W Qin, L Qiao, M Gao, M Zhou… - Advanced …, 2023 - Wiley Online Library
Immunotherapy is considered to be an effective treatment for cancer and has drawn
extensive interest. Nevertheless, the insufficient antigenicity and immunosuppressive tumor …

TME-related biomimetic strategies against cancer

C Peng, Y Xu, J Wu, D Wu, L Zhou… - International Journal of …, 2024 - Taylor & Francis
The tumor microenvironment (TME) plays an important role in various stages of tumor
generation, metastasis, and evasion of immune monitoring and treatment. TME targeted …

Immunogenic Extracellular Vesicles Derived from Endoplasmic Reticulum-Stressed Tumor Cells: Implications as the Therapeutic Cancer Vaccine

KH Han, CH Kim, SH Kim, CH Lee, M Park, VD Bui… - ACS …, 2023 - ACS Publications
Tumor-derived extracellular vesicles (TDEs) have potential for therapeutic cancer vaccine
applications since they innately possess tumor-associated antigens, mediate antigen …

Enhancing the anticancer immune response with the assistance of drug repurposing and delivery systems

Z Fu, X Zhang, Y Gao, J Fan… - Clinical and Translational …, 2023 - Wiley Online Library
Background The immune system plays a pivotal role in the initiation, evolution, invasion and
metastasis of cancer. Therapeutics aiming at modulating or boosting anticancer immune …

The battle within: cell death by phagocytosis in cancer

L Zhou, S Fan, W Zhang, Z Gong, D Wang… - Clinical and Translational …, 2024 - Springer
The process by which living cells are phagocytosed and digested to death is called cell
death by phagocytosis, a term that has just recently been generalized and redefined. It is …

Current Immunotherapy Techniques for Cancer Treatment: A Scoping Review

L Kreuder - Undergraduate Research in Natural and Clinical …, 2023 - urncst.com
Introduction: Immunotherapy, or the utilization of the immune system in fighting cancer, has
been of interest as of late. Many different immunotherapy strategies exist, such as modifying …