Transition metal-catalyzed coupling of heterocyclic alkenes via C–H functionalization: recent trends and applications

SV Kumar, S Banerjee, T Punniyamurthy - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Heterocyclic alkenes represent an important class of reactive feedstock and valuable
synthons for the synthesis of biologically important heterocyclic scaffolds. Although …

Transition metal-catalyzed double C vinyl–H bond activation: synthesis of conjugated dienes

VK Maikhuri, J Maity, S Srivastava… - Organic & Biomolecular …, 2022 - pubs.rsc.org
Conjugated dienes have occupied a pivotal position in the field of synthetic organic
chemistry and medicinal chemistry. They act as important synthons for the synthesis of …

Palladium-catalyzed C–H olefination of uridine, deoxyuridine, uridine monophosphate and uridine analogues

Q Zhao, R Xie, Y Zeng, W Li, G Xiao, Y Li, G Chen - RSC advances, 2022 - pubs.rsc.org
The palladium-catalyzed oxidative C–H olefinations of uridine, deoxyuridine, uridine
monophosphate and uridine analogues are reported herein. This protocol provides an …

Microwave-assisted modified synthesis of C8-analogues of naturally occurring methylxanthines: Synthesis, biological evaluation and their practical applications

BRK Shyamlal, M Mathur, DK Yadav, S Chaudhary - Fitoterapia, 2020 - Elsevier
An efficient, microwave-assisted, oxidant-interceded, transition-metal-free, cross-
dehydrogenative C sp 2-C sp 3 coupling of C 8-Caffeine 2/Theobromine 3/theophylline 4 …

Non‐Chelate‐Assisted Palladium‐Catalyzed Aerobic Oxidative Heck Reaction of Fluorobenzenes and Other Arenes: When Does the C− H Activation Need Help?

F Villalba, AC Albéniz - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
The pyridone fragment in the ligand [2, 2'‐bipyridin]‐6 (1H)‐one (bipy‐6‐OH) enables the
oxidative Heck reaction of simple arenes with oxygen as the sole oxidant and no redox …

MOFs extend the lifetime of Pd (II) catalyst for room temperature alkenylation of enamine‐like arenes

FG Cirujano, P Leo, J Vercammen… - Advanced Synthesis …, 2018 - Wiley Online Library
The synthesis of pharmaceutically relevant scaffolds, such as substituted indoles or uracils,
through the alkenylation of the “enamine‐like” aromatic C− H bond is performed at room …

Recent Advances in Palladium-Catalyzed Oxidative Couplings in the Synthesis/Functionalization of Cyclic Scaffolds Using Molecular Oxygen as the Sole Oxidant

AA Barboza, JA Dantas, MO Costa, A Chiavegatti… - …, 2022 - thieme-connect.com
Over the past years, Pd (II)-catalyzed oxidative couplings have enabled the construction of
molecular scaffolds with high structural diversity via C–C, C–N and C–O bond-forming …

Rhodium-Catalyzed Oxidative Annulation of 2-or 7-Arylindoles with Alkenes/Alkynes Using Molecular Oxygen as the Sole Oxidant Enabled by Quaternary Ammonium …

W Zhuang, J Zhang, Y Zheng, Q Huang - Molecules, 2021 - mdpi.com
Developing an efficient catalytic system using molecular oxygen as the oxidant for rhodium-
catalyzed cross-dehydrogenative coupling remains highly desirable. Herein, rhodium …

Tuning Catalytic Activity of Palladium in Direct C− H Arylation of Biologically Active Xanthines using Silver Additive.

P Thakur, Tinku, S Choudhary, M Patil - ChemistrySelect, 2024 - Wiley Online Library
We describe an efficient and versatile method for the direct C− H arylation of xanthines with
aryl halides using Pd/P (o‐tolyl) 3 as catalyst and Ag2O as an additive. Silver salts have …

Palladium‐Catalyzed C–H Olefination for Nucleic Acid Production

R Xie, Y Han, W Luo, Q Zhao, Y Li, G Chen - Current Protocols, 2023 - Wiley Online Library
The palladium‐catalyzed direct C–H olefination of unprotected uridine, 2′‐deoxyuridine,
uridine monophosphate, and uridine analogues are described here. This protocol provides …