Of men and mice: modeling the fragile X syndrome
R Dahlhaus - Frontiers in molecular neuroscience, 2018 - frontiersin.org
The Fragile X Syndrome (FXS) is one of the most common forms of inherited intellectual
disability in all human societies. Caused by the transcriptional silencing of a single gene, the …
disability in all human societies. Caused by the transcriptional silencing of a single gene, the …
The vertebrate genome: isochores and evolution.
G Bernardi - Molecular biology and evolution, 1993 - academic.oup.com
Vertebrate genomes are mosaics of isochores--namely, of long (> 300 kb), compositionally
homogeneous DNA segments that can be subdivided into a small number of families …
homogeneous DNA segments that can be subdivided into a small number of families …
Childhood abuse is associated with methylation of multiple loci in adult DNA
M Suderman, N Borghol, JJ Pappas… - BMC medical …, 2014 - Springer
Background Childhood abuse is associated with increased adult disease risk, suggesting
that processes acting over the long-term, such as epigenetic regulation of gene activity, may …
that processes acting over the long-term, such as epigenetic regulation of gene activity, may …
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
Two-thirds of gene promoters in mammals are associated with regions of non-methylated
DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation …
DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation …
Identification and High-Density Mapping of Gene-Rich Regions in Chromosome Group 5 of Wheat
The distribution of genes and recombination in the wheat genome was studied by
comparing physical maps with the genetic linkage maps. The physical maps were generated …
comparing physical maps with the genetic linkage maps. The physical maps were generated …
The human genome: organization and evolutionary history
G Bernardi - Annual review of genetics, 1995 - go.gale.com
The term genome was first introduced by German botanist Hans Winkler in the early 19th
century to describe the eukaryotic chromosome. It gained considerable attention through the …
century to describe the eukaryotic chromosome. It gained considerable attention through the …
The highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes.
S Saccone, A De Sario… - Proceedings of the …, 1992 - National Acad Sciences
Chromosome in situ suppression hybridization has been carried out on human metaphase
chromosomes to localize the G+ C-richest human DNA fraction (which only represents 3.5 …
chromosomes to localize the G+ C-richest human DNA fraction (which only represents 3.5 …
The biology of eukaryotic promoter prediction—a review
Computational prediction of eukaryotic promoters from the nucleotide sequence is one of the
most attractive problems in sequence analysis today, but it is also a very difficult one. Thus …
most attractive problems in sequence analysis today, but it is also a very difficult one. Thus …
Identification of sequence variants in genetic disease-causing genes using targeted next-generation sequencing
X Wei, X Ju, X Yi, Q Zhu, N Qu, T Liu, Y Chen, H Jiang… - PloS one, 2011 - journals.plos.org
Background Identification of gene variants plays an important role in research on and
diagnosis of genetic diseases. A combination of enrichment of targeted genes and next …
diagnosis of genetic diseases. A combination of enrichment of targeted genes and next …
The caste- and sex-specific DNA methylome of the termite Zootermopsis nevadensis
Epigenetic inheritance plays an important role in mediating alternative phenotype in highly
social species. In order to gain a greater understanding of epigenetic effects in societies, we …
social species. In order to gain a greater understanding of epigenetic effects in societies, we …