The ability of bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2) to inhibit bone
resorption has been known since the 1960s, but it is only recently that a detailed molecular …

Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …

Abstract The bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2, BPs) were first shown to
inhibit bone resorption in the 1960s, but it was not until 30 years later that a detailed …

Bisphosphonates are widely used in the treatment of diseases involving excessive bone
resorption, such as osteoporosis, cancer-associated bone disease, and Paget's disease of …

Applications of water-dispersible near-infrared (NIR)-emitting quantum dots (QDs) have
been hampered by their instability and low photoluminescence (PL) efficiencies. In this …

Bisphosphonates are effective antiresorptive agents owing to their bone‐targeting property
and ability to inhibit osteoclasts. It remains unclear, however, whether any non‐osteoclast …

Osteoclasts are giant polykaryons responsible for bone resorption. Because an
enhancement or loss of osteoclast function leads to bone diseases such as osteoporosis …

Introduction: Bisphosphonates (BPs) were introduced 45 years ago as anti-osteoporotic
drugs and during the last decade have been utilized as bone-targeting groups in systemic …

Bisphosphonates are widely used antiresorptive drugs that bind to calcium. It has become
evident that these drugs have differing affinities for bone mineral; however, it is unclear …

The review provides the first generalized and systematized information on the use of click
reactions in chitosan chemistry for the preparation of novel polymers with attractive …