The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity
Human longevity is a complex phenotype resulting from the combinations of context-
dependent gene-environment interactions that require analysis as a dynamic process in a …
dependent gene-environment interactions that require analysis as a dynamic process in a …
Genetics of human longevity within an eco-evolutionary nature-nurture framework
Human longevity is a complex trait, and to disentangle its basis has a great theoretical and
practical consequences for biomedicine. The genetics of human longevity is still poorly …
practical consequences for biomedicine. The genetics of human longevity is still poorly …
Ancient Rome: A genetic crossroads of Europe and the Mediterranean
Ancient Rome was the capital of an empire of~ 70 million inhabitants, but little is known
about the genetics of ancient Romans. Here we present 127 genomes from 29 …
about the genetics of ancient Romans. Here we present 127 genomes from 29 …
Ancient and recent admixture layers in Sicily and Southern Italy trace multiple migration routes along the Mediterranean
The Mediterranean shores stretching between Sicily, Southern Italy and the Southern
Balkans witnessed a long series of migration processes and cultural exchanges …
Balkans witnessed a long series of migration processes and cultural exchanges …
Deep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR mutation rates on the human Y-chromosome and reveals migrations of Iranic …
O Balanovsky, M Zhabagin, A Agdzhoyan… - PLoS …, 2015 - journals.plos.org
Y-chromosomal haplogroup G1 is a minor component of the overall gene pool of South-
West and Central Asia but reaches up to 80% frequency in some populations scattered …
West and Central Asia but reaches up to 80% frequency in some populations scattered …
The Italian genome reflects the history of Europe and the Mediterranean basin
Recent scientific literature has highlighted the relevance of population genetic studies both
for disease association mapping in admixed populations and for understanding the history …
for disease association mapping in admixed populations and for understanding the history …
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans
Background The cline of human genetic diversity observable across Europe is recapitulated
at a micro-geographic scale by variation within the Italian population. Besides resulting from …
at a micro-geographic scale by variation within the Italian population. Besides resulting from …
Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula
The Italian peninsula has long represented a natural hub for human migrations across the
Mediterranean area, being involved in several prehistoric and historical population …
Mediterranean area, being involved in several prehistoric and historical population …
The mitogenome portrait of Umbria in Central Italy as depicted by contemporary inhabitants and pre-Roman remains
A Modi, H Lancioni, I Cardinali, MR Capodiferro… - Scientific reports, 2020 - nature.com
Umbria is located in Central Italy and took the name from its ancient inhabitants, the Umbri,
whose origins are still debated. Here, we investigated the mitochondrial DNA (mtDNA) …
whose origins are still debated. Here, we investigated the mitochondrial DNA (mtDNA) …
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ
N Solé-Morata, P Villaescusa, C García-Fernández… - Scientific reports, 2017 - nature.com
Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main
branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in …
branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in …