Antibody-mediated rejection of solid-organ allografts

A Loupy, C Lefaucheur - New England Journal of Medicine, 2018 - Mass Medical Soc
Antibody-Mediated Rejection of Solid-Organ Allografts This review focuses on current
standards for management of antibody-mediated rejection in solid-organ transplant …

Age and liver transplantation

F Durand, J Levitsky, F Cauchy, H Gilgenkrantz… - Journal of …, 2019 - Elsevier
The average age of liver transplant donors and recipients has increased over the years.
Independent of the cause of liver disease, older candidates have more comorbidities, higher …

[PDF][PDF] Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study …

CL Mack, D Adams, DN Assis, N Kerkar… - …, 2020 - Wiley Online Library
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …

[HTML][HTML] Liver transplantation outcomes from controlled circulatory death donors: SCS vs in situ NRP vs ex situ NMP

R Gaurav, AJ Butler, V Kosmoliaptsis… - Annals of …, 2022 - journals.lww.com
Objective: To compare the outcomes of livers donated after circulatory death (DCD) and
undergoing either in situ normothermic regional perfusion (NRP) or ex situ normothermic …

[HTML][HTML] Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by …

JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

International liver transplantation society consensus statement on immunosuppression in liver transplant recipients

M Charlton, J Levitsky, B Aqel, J O'Grady… - …, 2018 - journals.lww.com
Effective immunosupression management is central to achieving optimal outcomes in liver
transplant recipients. Current immunosuppression regimens and agents are highly effective …

[HTML][HTML] The immunological basis of liver allograft rejection

V Ronca, G Wootton, C Milani, O Cain - Frontiers in immunology, 2020 - frontiersin.org
Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …

[HTML][HTML] Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD

E Smirnova, MD Muthiah, N Narayan, MS Siddiqui… - Hepatology, 2022 - journals.lww.com
Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

[PDF][PDF] The role of complement in liver injury, regeneration, and transplantation

EB Thorgersen, A Barratt‐Due, H Haugaa… - …, 2019 - Wiley Online Library
The liver is both an immunologically complex and a privileged organ. The innate immune
system is a central player, in which the complement system emerges as a pivotal part of liver …

[HTML][HTML] Clinical recommendations for posttransplant assessment of anti–HLA (Human Leukocyte Antigen) donor-specific antibodies: A Sensitization in …

C Lefaucheur, K Louis, AB Morris, JL Taupin… - American Journal of …, 2023 - Elsevier
Abstract Although anti–HLA (Human Leukocyte Antigen) donor-specific antibodies (DSAs)
are commonly measured in clinical practice and their relationship with transplant outcome is …