Head and neck cancers include neoplasms of the oral cavity, pharynx, and larynx. The risk
of these cancers is strongly associated with smoking and alcohol ingestion. There have …

Introduction Oral cancer is one of the most common cancers and it constitutes a major health
problem particularly in developing countries. It is one of the leading causes of death …

In late 1993 and early 1994, two distinct lines of research converged on a new tumor
suppressor gene located on human chromosome 9p21. The órst report was of the existence …

Emerging evidence suggests that microRNA, which are well‐conserved, abundant and
small regulatory RNA, may be involved in the pathogenesis of human cancers. We recently …

Microsatellite DNA alterations are an integral part of neoplastic progression and are
valuable as clonal markers for the detection of human cancers1–3. Moreover, recent …

Background Surgical oncologists rely heavily on the histopathological assessment of
surgical margins to ensure total excision of the tumor in patients with head and neck cancer …

Lung cancer is the most common cause of cancer death in developed countries. The
prognosis is poor, with less than 15% of patients surviving 5 years after diagnosis. The poor …

The present invention relates to the detection of nucleic acid sequence differences using
coupled ligase detection reaction and polymerase chain reaction. One aspect of the present …

Five percent of all tumors occur in the head and neck, and approximately half of those occur
specifically in the oral cavity. Of the 615,000 new cases of oral cavity tumors reported …

One of the best approaches to identifying genetic changes critical to oral cancer progression
is to compare progressing and nonprogressing oral premalignant lesions. However, such …