Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Angiotensin-converting enzyme inhibitors

NJ Brown, DE Vaughan - Circulation, 1998 - Am Heart Assoc
ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and
renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive …

[HTML][HTML] Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: a systematic review and meta-analysis

K Kalam, TH Marwick - European journal of cancer, 2013 - Elsevier
Background Cardiotoxicity is a well-recognised complication of chemotherapy with
anthracycline and/or trastuzumab, and its prevention remains an important challenge in …

Reversal of left ventricular hypertrophy in hypertensive patients: a metaanalysis of 109 treatment studies

B Dahlöf, K Pennert, L Hansson - 1992 - academic.oup.com
This is a metaanalysis of all available studies as of December 1990 that have evaluated the
effect of antihypertensive pharmacologic therapy on left ventricular structure examined by …

Cytoplasmic signaling pathways that regulate cardiac hypertrophy

JD Molkentin, GW Dorn II - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract This review discusses the rapidly progressing field of cardiomyocyte signal
transduction and the regulation of the hypertrophic response. When stimulated by a wide …

Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection.

EM Lonn, S Yusuf, P Jha, TJ Montague, KK Teo… - Circulation, 1994 - Am Heart Assoc
A ngiotensin-converting enzyme (ACE) inhibitors are commonly used drugs in the
management of a variety of cardiovascular diseases. They are effective antihypertensive …

Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study

P Gosse, DJ Sheridan, F Zannad… - Journal of …, 2000 - journals.lww.com
Objective To compare the efficacy of indapamide sustained release (SR) 1.5 mg and
enalapril 20 mg at reducing left ventricular mass index (LVMI) in hypertensive patients with …

Effect of high-versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure

L Gullestad, P Aukrust, T Ueland, T Espevik… - Journal of the American …, 1999 - jacc.org
OBJECTIVES We examined the effect of long-term treatment with two doses of the
angiotensin converting enzyme (ACE) inhibitor enalapril on various immunological variables …

Enalapril: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

PA Todd, RC Heel - Drugs, 1986 - Springer
Synopsis: Enalapril maleate 1 is an orally active angiotensin-converting enzyme inhibitor. It
lowers peripheral vascular resistance without causing an increase in heart rate. Enalapril 10 …

Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats

S Kim, K Ohta, A Hamaguchi, T Yukimura, K Miura… - …, 1995 - Am Heart Assoc
Cardiac phenotypic modulation and remodeling appear to be involved in the
pathophysiology of cardiac hypertrophy and heart failure. We undertook this study to …